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Hello, Doctor: May I ask what "ammonia" refers to? My father is around 60 years old and sometimes experiences confusion at night, and he also talks in his sleep.
He has seen a doctor who mentioned that elevated ammonia levels could be the cause.
I would like to ask if there are any other treatment methods and preventive measures besides medication.
Also, what is it, and why does this happen? Thank you.
Cai, 20~29 year old female. Ask Date: 2005/01/29
Dr. Huang Maosen reply Smoking Cessation
Hello! Ammonia is the English name for "氨." After protein is broken down in the human body, ammonia is produced.
When liver function is normal, the excess ammonia can be excreted from the body.
However, when liver function deteriorates, the ability to clear ammonia is impaired, leading to accumulation in the body, which can cause confusion and even coma.
Prevention involves reducing the intake of high-protein foods.
Treatment, in addition to medication, must address the underlying diseases that cause the increase in ammonia levels.
Thank you!
Reply Date: 2005/01/29
More Info
Ammonia, in the context of health, typically refers to a compound that can accumulate in the body, particularly in individuals with liver dysfunction. Elevated ammonia levels can lead to a condition known as hepatic encephalopathy, which can cause symptoms such as confusion, altered mental status, and even coma. This condition arises when the liver is unable to effectively process ammonia, a byproduct of protein metabolism, leading to its accumulation in the bloodstream.
In your father's case, his symptoms of confusion and sleep talking may indeed be linked to elevated ammonia levels. The liver plays a crucial role in detoxifying ammonia, converting it into urea, which is then excreted through urine. When the liver is compromised, such as in cases of cirrhosis or severe liver disease, ammonia can build up, leading to neurological symptoms.
While medication is often the primary treatment for managing elevated ammonia levels—such as lactulose, which helps to reduce ammonia absorption in the intestines—there are also non-medical approaches that can be beneficial. Here are some strategies that may help manage ammonia levels and improve overall liver health:
1. Dietary Modifications: A diet low in protein may help reduce ammonia production, as protein metabolism generates ammonia. However, it's essential to consult with a healthcare provider or a dietitian before making significant dietary changes, as protein is still necessary for overall health.
2. Hydration: Ensuring adequate fluid intake can help the kidneys excrete waste products more effectively, including ammonia. Staying well-hydrated is crucial, especially for individuals with liver issues.
3. Regular Monitoring: Regular check-ups with a healthcare provider can help monitor liver function and ammonia levels. This allows for timely interventions if levels begin to rise.
4. Avoiding Alcohol: Alcohol can exacerbate liver damage and should be avoided entirely in individuals with liver dysfunction. This can help preserve liver function and reduce the risk of ammonia accumulation.
5. Exercise: Engaging in regular, moderate exercise can improve overall health and may help support liver function. However, it's essential to tailor exercise regimens to the individual's capabilities and health status.
6. Managing Underlying Conditions: Conditions such as diabetes or obesity can contribute to liver disease. Managing these conditions through lifestyle changes can help improve liver health and reduce the risk of elevated ammonia levels.
7. Avoiding Certain Medications: Some medications can worsen liver function or interact negatively with liver metabolism. Always consult with a healthcare provider before starting or stopping any medications.
8. Mental Health Support: Given the cognitive symptoms your father is experiencing, it may be beneficial to seek support for mental health. Cognitive behavioral therapy or counseling can help manage the psychological aspects of dealing with chronic health issues.
In summary, while medications are often necessary to manage elevated ammonia levels, lifestyle modifications, dietary changes, and regular medical supervision can also play a significant role in treatment and prevention. It’s crucial to work closely with healthcare professionals to develop a comprehensive plan tailored to your father's specific needs and health status.
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