Ponstan: Its Role in Fever and Pain Management - Internal Medicine

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Anti-inflammatory agents


Ponstan, also known as Mefenamic Acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for pain relief and to reduce inflammation.
While it is not specifically indicated for treating fever, it can have a mild antipyretic effect, which means it may help lower fever as a secondary benefit.
Its main uses include pain management for conditions such as traumatic injuries, headaches, dental pain, postoperative pain, postpartum pain, and rheumatic musculoskeletal pain.
If you have concerns about your treatment or symptoms, it's best to consult your healthcare provider for personalized advice.

pp, 20~29 year old female. Ask Date: 2005/03/16

Dr. Zheng Shuxing reply Internal Medicine


Hello: This question is too brief.
When seeking medical attention for a fever, it is essential to first have a physical examination followed by necessary laboratory tests to determine the underlying condition.
Ponstan is not an antimicrobial agent; it is classified as an anti-inflammatory drug that can reduce inflammation, alleviate pain, and lower fever.
Zheng Shuxin.

Reply Date: 2005/03/16

More Info


Ponstan, known generically as Mefenamic Acid, is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic (pain-relieving) and anti-inflammatory properties. It is commonly prescribed for conditions such as menstrual pain, dental pain, and other types of acute pain. While it is not classified as a traditional antipyretic (fever-reducing) medication like acetaminophen or ibuprofen, it does possess some ability to reduce fever due to its anti-inflammatory effects.

When you visit a doctor for a fever, the underlying cause of the fever is crucial in determining the appropriate treatment. Fever is often a symptom of an underlying infection or inflammatory process, and while Ponstan can help alleviate discomfort associated with pain and inflammation, it does not directly target the underlying cause of the fever. Instead, it may help to lower the fever as a secondary effect of its anti-inflammatory action.

The mechanism by which Ponstan works involves the inhibition of cyclooxygenase (COX) enzymes, which play a key role in the production of prostaglandins. Prostaglandins are compounds that promote inflammation, pain, and fever. By reducing the levels of these compounds, Ponstan can help alleviate pain and may also contribute to a reduction in fever. However, it is important to note that while Ponstan can provide symptomatic relief, it does not treat the root cause of the fever, such as an infection.

In terms of side effects, Ponstan can cause various adverse reactions, including gastrointestinal issues, allergic reactions, and, in some cases, edema (swelling). As noted in your inquiry, some individuals may experience allergic reactions, which can manifest as swelling, redness, or other symptoms. If you have a history of allergies, particularly to other NSAIDs or aspirin, it is crucial to inform your healthcare provider before taking Ponstan.

In summary, while Ponstan can help manage pain and may have a mild effect on reducing fever, it is not primarily indicated for treating fever. If you are experiencing persistent fever, it is essential to follow up with your healthcare provider to determine the underlying cause and receive appropriate treatment. Always consult with your doctor regarding any concerns about medications, especially if you have experienced adverse reactions in the past. Your health and safety should always be the top priority when managing symptoms like fever and pain.

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