Lymph Node Swelling: Causes and Concerns - Internal Medicine

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Enlargement of the lymph nodes in the posterior neck?


I have noticed two asymmetrical small lumps on the back sides of my neck, which feel soft and movable.
They become visible when I turn my head to the sides, and they are about 1 cm in size.
This condition has been present for approximately 3 to 4 days.
I have been taking sleep medication and anti-anxiety medication for about 5 months, including Efexor XR, Ativan, Mesyrel, Thru, and Stilnox.
I reduced the dosage of Ativan by half (to 1 mg) 10 days ago.
Five days ago, I noticed that I was sweating a lot at night while sleeping, but I do not have any obvious cold symptoms.
I am unsure if this is a side effect of long-term medication use or if there is a problem with lymphadenopathy.

chris, 30~39 year old female. Ask Date: 2005/04/19

Dr. Yang Hongzhi reply Internal Medicine


There may be a condition of lymphadenopathy, and the medication does not seem to have much relevance.
If the symptoms persist, it may be advisable to consider seeing an otolaryngologist.

Reply Date: 2005/04/19

More Info


Lymph node swelling, particularly in the neck area, can be a source of concern for many individuals. The presence of soft, movable lumps that are asymmetrical, as you described, can often be attributed to a variety of causes, ranging from benign to more serious conditions. Given your recent experience with medication for anxiety and sleep issues, it’s important to consider both the potential side effects of these medications and the underlying causes of lymphadenopathy (swelling of lymph nodes).

Firstly, lymph nodes are part of the immune system and play a crucial role in fighting infections. They can swell in response to various stimuli, including infections (viral or bacterial), inflammation, or malignancies. In your case, the fact that the lymph nodes are soft and movable is generally a reassuring sign, as hard, fixed lymph nodes are more concerning for malignancy. However, the duration of the swelling (3-4 days) and the asymmetry should still prompt further evaluation.

The medications you are taking, particularly Ativan (lorazepam), can have side effects, but they are not typically associated with lymph node swelling. However, the reduction in dosage may lead to withdrawal symptoms, which can include increased anxiety, sweating, and other physical symptoms. The sweating you experienced could be related to the medication adjustment or a response to anxiety rather than a direct cause of lymphadenopathy.

It is also worth noting that anxiety itself can lead to physical symptoms, including muscle tension and increased awareness of bodily sensations, which may make you more sensitive to changes in your body, such as the presence of lymph nodes. This heightened awareness can sometimes lead to increased concern about benign findings.

Given your symptoms and the recent changes in your medication, it would be prudent to consult with a healthcare provider. They can perform a physical examination and may recommend further tests, such as blood tests or imaging studies, to determine the cause of the lymph node swelling. It’s essential to rule out any infections or other underlying conditions that may require treatment.

In summary, while the soft, movable nature of the lymph nodes is generally a good sign, the recent changes in your medication and the presence of other symptoms warrant a thorough evaluation by a healthcare professional. They can provide you with the appropriate guidance and reassurance, as well as address any concerns regarding your medications and their side effects. Regular follow-ups and open communication with your healthcare provider are key to managing your health effectively.

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