Is It Safe for My 3-Month-Old to Take Polaramine? - Pediatrics

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Can I take this medication?


I have a three-month-old child who has a cold and saw an ENT doctor.
The doctor prescribed Polaramine 0.9 mg, Bilastine 0.9 mg to be taken four times a day, and Lysozyme 100 mg.
I checked and found that Polaramine is not recommended for children under two years old.
If my child has taken it, could there be any issues? Thank you!

Lin, 20~29 year old female. Ask Date: 2005/04/27

Dr. Liang Hongjian reply Pediatrics


Thank you, Ms.
Lin, for your letter.
In your message, you inquired about Polaramine 0.9, which is formally known as Dexchlorpheniramine maleate.
We commonly refer to it as dexchlorpheniramine.
CTM is an older medication that acts as an antihistamine, while dexchlorpheniramine is a more recently developed drug aimed at reducing drowsiness as a side effect.
Generally, it has a very high safety profile.
Antihistamines with age restrictions primarily consist of larger molecule antihistamines, with Loratadine being a common example.
When taking these larger molecule antihistamines, there have been reports in the literature indicating that co-administration with certain antibiotics (such as Erythromycin) may potentially lead to cardiac issues, such as arrhythmias.

Reply Date: 2005/04/27

More Info


When it comes to administering medications to infants, caution is paramount. Polaramine, which contains the active ingredient dexchlorpheniramine, is an antihistamine that is often used to relieve allergy symptoms. However, its use in very young children, particularly those under the age of two, is generally discouraged due to the potential for adverse effects.

In your case, your three-month-old child has been prescribed Polaramine along with other medications. It's important to note that the safety and efficacy of antihistamines in infants have not been thoroughly established. The American Academy of Pediatrics (AAP) advises against the use of over-the-counter cough and cold medications in children under the age of four, and this includes antihistamines like Polaramine. The reason for this caution is that young children can be particularly sensitive to the side effects of these medications, which can include sedation, irritability, and in some cases, paradoxical reactions where the child becomes more agitated rather than calm.

If your child has already been prescribed Polaramine, it is crucial to follow up with your pediatrician or the prescribing physician. They can provide guidance on the appropriateness of this medication for your child's specific condition and age. If you have concerns about the prescription, do not hesitate to express them to your healthcare provider. They may consider alternative treatments that are safer for infants.

In terms of potential problems from taking Polaramine, side effects can vary. Common side effects of antihistamines in children may include drowsiness, dry mouth, dizziness, and gastrointestinal disturbances. In some cases, particularly in very young children, there can be more severe reactions, including respiratory depression or increased heart rate. If you notice any unusual symptoms or if your child seems excessively sleepy or irritable after taking the medication, it is essential to seek medical attention immediately.

Additionally, the other medications prescribed, such as lysozyme, are generally considered safer for infants, but it's still important to monitor your child for any adverse reactions. Always ensure that any medication given to an infant is done under the guidance of a healthcare professional who is aware of the child's medical history and current health status.

In summary, while Polaramine may have been prescribed, it is crucial to consult with your pediatrician regarding its safety for your three-month-old. They can provide the best advice tailored to your child's health needs and may suggest alternative treatments that are more appropriate for their age. Always prioritize safety and open communication with healthcare providers when it comes to the health of your child.

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