Pediatric Medication Safety and Newborn Screening: What Parents Should Know

Medication consultation & neonatal ultrasound examination, hearing screening?

Hello Doctor: My son is currently three months old (born on January 31).
Last week, he had a severe cold with nasal congestion, so we took him to a nearby pediatric clinic for treatment.
The doctor prescribed the following medications: 1.
Periactin: Total dosage 2; per dose 0.17; four times a day for three days.
2.
Biofermin: Total dosage 4; per dose 0.33; four times a day for three days.
3.
Gascon: Total dosage 2; per dose 0.17; four times a day for three days.
4.
KBT: Total dosage 2; per dose 0.17; four times a day for three days.
I have heard that giving medications to such a young child can have adverse effects on the kidneys or other metabolic organs.
Is this true? Could the medications and dosages prescribed above cause any negative effects or side effects? Additionally, regarding the out-of-pocket neonatal ultrasound examinations (heart, brain, abdomen) and hearing screening, is it still possible to conduct these tests since the child is already three months old? I would appreciate your clarification on these matters.
Thank you.

PP, 30~39 year old female. Ask Date: 2007/04/24

Dr. Pei Rensheng reply Pediatrics

Hello! For a three-month-old baby weighing 6 kilograms, based on the principle of 40 kilograms per dose, the dosage should be approximately 1/6 to 1/7.
Therefore, the dosages for Gascon (for gas relief) and Periactin (for appetite stimulation and treating runny nose) are appropriate, while the dosage for Biofermin (for intestinal health) can be higher.
It seems that the prescriptions from the pediatric clinic are acceptable! Appropriate medications and correct dosages will not adversely affect the child's kidneys or other metabolic organs, so you can rest assured.

Regarding the out-of-pocket neonatal ultrasound examinations (heart, brain, abdomen) and hearing screening, it is still possible to conduct these tests since the child is three months old.
The main purpose is to check for congenital heart disease, hydrocephalus, hydronephrosis, or other deformities, as some deformities may not present any symptoms initially.
Of course, it is also acceptable to wait until the well-child visit when the physician may notice any issues.

In 1982, the American Joint Committee on Hearing Screening proposed seven risk criteria, and it is preferable to conduct the screening before the child is six months old.
These criteria include:
1.
A family history of hearing impairment.

2.
Congenital infections (such as syphilis, rubella, etc.).

3.
Physiological deformities (including ear, nose, throat, and head/neck deformities).

4.
Birth weight less than 1500 grams.

5.
Elevated bilirubin levels (jaundice).

6.
Bacterial meningitis.

7.
Hypoxia at birth, low Apgar score.

This information is provided for your consideration regarding hearing screening.
Wishing you health, happiness, and all the best! Sincerely, Dr.
Pei Ren.

Reply Date: 2007/04/24

More Info

When it comes to pediatric medication safety and newborn screening, it is essential for parents to be well-informed and proactive in ensuring their child's health. Your concerns regarding the medications prescribed for your three-month-old son, as well as the timing for newborn screenings, are valid and important.

Firstly, regarding the medications prescribed: Periactin (Cyproheptadine), Biofermin, Gascon, and KBT are commonly used in pediatric care for various conditions. Periactin is an antihistamine that can help alleviate allergy symptoms, while Biofermin is a probiotic that supports gut health. Gascon is typically used for gas relief, and KBT is often prescribed for cough and cold symptoms. The dosages provided seem to be within the acceptable range for a child of his age and weight, assuming he weighs around 6 kg.
Concerns about the impact of medications on the kidneys and metabolic organs in young children are understandable. However, when prescribed by a qualified pediatrician and administered at the correct dosages, these medications should not pose significant risks to your child's health. Pediatricians carefully consider the benefits and potential risks when prescribing medications, especially for infants. It is crucial to follow the prescribed dosages and monitor your child for any adverse reactions. If you notice any unusual symptoms or side effects, do not hesitate to contact your healthcare provider.

As for the newborn screening tests, it is never too late to conduct these assessments, even at three months of age. Newborn screenings, including echocardiograms for heart conditions, cranial ultrasounds for brain abnormalities, abdominal ultrasounds, and hearing tests, are essential for identifying congenital issues that may not present symptoms initially. Early detection can significantly improve outcomes for various conditions. If your child has not yet undergone these screenings, you should discuss scheduling them with your pediatrician. They can provide guidance on the appropriate tests based on your child's health history and any concerns you may have.

In summary, while it is natural to worry about the effects of medications on a young child, the prescribed medications appear to be appropriate for your son's condition. Always ensure that you are following the prescribed dosages and keep an eye out for any side effects. Additionally, do not hesitate to pursue necessary screenings for your child, as early detection of potential health issues can lead to better management and outcomes. Regular communication with your pediatrician is key to navigating your child's health and ensuring their well-being.

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