Impact of Antithyroid Medications on Birth Control Effectiveness - Obstetrics and Gynecology

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Birth control pills and antithyroid medications?


Hello Doctor, I would like to ask you a question.
I have hyperthyroidism and was not taking medication initially, but it has recently relapsed, and I need to start medication again.
I would like to consult with you regarding this.
I am currently taking the birth control pill Diane 21.
Will taking the antithyroid medications affect the effectiveness of the birth control pill? The antithyroid medications I am taking are Lica 5mg and Inderal 40mg.

Mei Mei, 20~29 year old female. Ask Date: 2005/05/18

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: The contraceptive effectiveness of birth control pills is not 100%.
If taken consistently, you can achieve up to a 98% effectiveness rate.
If you are concerned, you may also use condoms for added protection.
Hsinchu City Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2005/05/18

More Info


When it comes to the interaction between antithyroid medications and birth control pills, it is essential to understand how these medications work and their potential effects on contraceptive efficacy. In your case, you are taking the birth control pill "Diane 21" while also needing to start antithyroid medications such as Lica (likely referring to a medication containing lithium or a similar compound) and Inderal (propranolol).

First, let's clarify the primary function of these medications. Antithyroid medications, such as those used to manage hyperthyroidism, work by inhibiting the production of thyroid hormones. Propranolol, on the other hand, is a beta-blocker often used to manage symptoms of anxiety or rapid heart rate associated with hyperthyroidism. Neither of these medications is known to have a significant impact on the effectiveness of hormonal contraceptives like Diane 21.

Research indicates that most antithyroid medications do not interfere with the metabolism of estrogen and progestin, the active components of many birth control pills. Therefore, the likelihood of these medications affecting the contraceptive efficacy of Diane 21 is low. However, it is crucial to consider individual variations in metabolism and the potential for other factors to influence the effectiveness of birth control.

For instance, certain medications can induce liver enzymes that metabolize hormonal contraceptives more quickly, potentially reducing their effectiveness. However, antithyroid medications like Lica and Inderal are not typically associated with such enzyme induction. Therefore, you should not expect a significant reduction in the effectiveness of your birth control pill while taking these medications.

That said, it is always advisable to consult with your healthcare provider regarding any concerns about medication interactions. They can provide personalized advice based on your medical history and current health status. Additionally, if you experience any side effects or changes in your menstrual cycle while taking these medications, it is essential to discuss these with your doctor, as they may indicate a need for further evaluation or adjustment of your treatment plan.

In summary, based on current medical knowledge, taking antithyroid medications like Lica and Inderal should not significantly impact the effectiveness of your birth control pill, Diane 21. However, always keep an open line of communication with your healthcare provider to ensure that you are managing both your thyroid condition and your contraceptive needs effectively. Regular follow-ups and monitoring are crucial, especially when dealing with hormonal treatments and thyroid issues.

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