Should I Stop My Immunomodulator or Flexeril for Arthritis? - Orthopedics

Share to:

Immunomodulators


I am currently taking Ropinirole, but recently my doctor prescribed me an immunomodulator due to arthritis.
I noticed in the drug dictionary that both medications can affect sperm.
Should I stop one of these medications?

kezu, 20~29 year old female. Ask Date: 2005/06/15

Dr. Lin Xiaoyi reply Orthopedics


Hello: Finasteride inhibits male hormones to improve male pattern baldness, which may have a minimal impact on male sexual function and sperm count, but this is rare and can recover after discontinuation.
When taking immunomodulators for arthritis, the effects depend on the specific type of immunomodulator; some may cause teratogenic effects, while others may only affect sperm production and fertility.
May I ask which medication you are taking? Immunomodulators should not be discontinued casually; you must discuss this with your physician before stopping the medication.
Sincerely, Lin Hsiao-Yi, Department of Allergy, Immunology, and Rheumatology, Taipei Veterans General Hospital.

Reply Date: 2005/06/15

More Info


When considering whether to stop your immunomodulator or Flexeril (cyclobenzaprine) for arthritis, it’s essential to consult with your healthcare provider, as they can provide personalized advice based on your medical history and current condition. However, I can provide some general information regarding these medications and their potential effects.

Understanding the Medications:
1. Immunomodulators: These medications are designed to modify the immune system's response. They are often used in autoimmune conditions, such as rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), to reduce inflammation and prevent the immune system from attacking the body’s own tissues. Common immunomodulators include methotrexate, azathioprine, and mycophenolate mofetil. While these medications can be effective in managing symptoms and preventing joint damage, they may have side effects, including potential impacts on fertility and sperm production.

2. Flexeril (Cyclobenzaprine): This is a muscle relaxant that is often prescribed to relieve muscle spasms and associated pain. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Flexeril is typically used for short-term relief and is not intended for long-term use. While it is generally considered safe, it can cause drowsiness and other side effects.

Concerns About Fertility:
Both immunomodulators and Flexeril have been associated with potential effects on fertility, particularly in men. Immunomodulators can impact sperm production and quality, while Flexeril's effects on fertility are less clear but could potentially contribute to issues if used in high doses or for extended periods.

Should You Stop One of the Medications?
1. Consult Your Doctor: The first step is to have a thorough discussion with your healthcare provider. They can assess your specific situation, including the severity of your arthritis, the effectiveness of your current treatment regimen, and any concerns regarding fertility.
2. Evaluate the Necessity of Each Medication: If your arthritis is well-controlled with the immunomodulator, your doctor may suggest continuing it while monitoring any side effects. If Flexeril is only being used occasionally for muscle spasms, it might be possible to reduce or stop it without significantly impacting your arthritis management.

3. Consider Alternative Treatments: If fertility is a significant concern, your doctor may suggest alternative treatments for managing arthritis that have a lower risk of affecting sperm quality. These could include non-steroidal anti-inflammatory drugs (NSAIDs) or physical therapy.

4. Monitor Your Symptoms: If you decide to stop or reduce one of the medications, closely monitor your symptoms. If you experience increased pain or inflammation, it may be necessary to adjust your treatment plan.

5. Fertility Consultation: If you are actively trying to conceive or have concerns about fertility, consider consulting a fertility specialist. They can provide additional insights and recommendations tailored to your situation.

Conclusion:
In summary, the decision to stop or continue either your immunomodulator or Flexeril should be made in collaboration with your healthcare provider. They will consider the benefits and risks of each medication in the context of your overall health and treatment goals. Open communication about your concerns, including those related to fertility, will help ensure that you receive the most appropriate care for your arthritis while addressing any potential side effects.

Similar Q&A

Managing Rheumatoid Arthritis: Can Rehab Replace Medication?

My sister was diagnosed with rheumatoid arthritis by her doctor, who prescribed corticosteroids and recommended physical therapy. She is currently experiencing less pain. Is it possible for her to only continue with physical therapy and stop taking the medication? Thank you!


Dr. Chen Xianchang reply Rehabilitation
Hello, sir: Thank you for your inquiry. Here are my responses and suggestions: 1. In practical terms, rheumatoid arthritis often involves repetitive movements that can lead to joint damage, which may necessitate the use of corticosteroids, indicating multiple flare-ups. Typical...

[Read More] Managing Rheumatoid Arthritis: Can Rehab Replace Medication?


Medication vs. Biologics: Which is Better for Ankylosing Spondylitis?

Hello Doctor, my son is 20 years old and has been diagnosed with ankylosing spondylitis for 3.5 years. It took 1.5 years after the onset of symptoms to confirm the diagnosis and begin formal treatment. The overview of his treatment over the past two years is as follows: In the fi...


Dr. Zeng Guosen reply Internal Medicine
The general principle is that traditional oral medications are the first-line treatment. If the condition is stable, the use of biologics is not recommended. It may be worth considering a reduction in medication and monitoring the situation. Biologics are also a type of medicatio...

[Read More] Medication vs. Biologics: Which is Better for Ankylosing Spondylitis?


Understanding Psoriatic Arthritis: Treatment Options and Concerns

Hello Doctor, last year I experienced pain in my right wrist and consulted a physician at Kaohsiung Medical University Hospital. The doctor informed me that it might be psoriatic arthritis. I have been taking medication for over a year (for the first four months, I was on Janus k...


Dr. Gao Jiankai reply Internal Medicine
Hello, thank you for your question. Here are my responses: 1. I researched online and feel that my symptoms are very similar to rheumatoid arthritis, but during my initial consultation, the anti-citrullinated protein antibody test came back normal. The doctor said it is not rhe...

[Read More] Understanding Psoriatic Arthritis: Treatment Options and Concerns


Do You Have to Take Medication for Life with Rheumatoid Arthritis?

I have been diagnosed with Lyme disease, which I know cannot be cured. I initially thought that I could take medication only during flare-ups and then stop, but I have been taking it for six months now. The doctor said there is no inflammation, yet I still need to take four immun...


Dr. Gao Jiankai reply Internal Medicine
Hello, thank you for your question. It is possible to discontinue medication for Still's disease as long as the inflammatory markers are consistently normal during regular follow-ups; some physicians may attempt to stop the medication. However, during the management of Still...

[Read More] Do You Have to Take Medication for Life with Rheumatoid Arthritis?


Related FAQ

Rheumatoid Arthritis

(Orthopedics)

Ankylosing Spondylitis

(Orthopedics)

Degenerative Arthritis

(Orthopedics)

Arthritis

(Internal Medicine)

Humerus

(Orthopedics)

Osteomyelitis

(Orthopedics)

Ankylosing Spondylitis

(Internal Medicine)

Wrist

(Orthopedics)

Muscle Pain

(Orthopedics)

Artificial Hip Joint

(Orthopedics)