Can SLE and Steroid Use in Fathers Affect Baby's Health? - Obstetrics and Gynecology

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Congenital anomaly


Hello, I would like to ask if a man with systemic lupus erythematosus (SLE) who has been taking steroids for three and a half years, at a dosage of 1-2 pills daily, could cause his wife to give birth to a child with congenital abnormalities.
Additionally, if the man had two X-rays of his arm in the same month and took pain relievers and cold/cough medication while his wife was pregnant, is there a risk of having a child with congenital abnormalities?

kelly, 30~39 year old female. Ask Date: 2001/06/15

Dr. Zhan Deqin reply Obstetrics and Gynecology


1.
No, pregnant women may sometimes need to use steroids.
2.
No, the fetus is more susceptible to effects during the first twelve weeks after conception, and the radiation from one or two X-rays is actually quite low.
Additionally, cold medications are not toxic enough to cause deformities from taking a few doses.

Reply Date: 2001/06/15

More Info


When considering the health of a baby in relation to a father's health conditions and medication use, particularly in the context of Systemic Lupus Erythematosus (SLE) and steroid use, it is essential to understand the implications of these factors. SLE is an autoimmune disease that can affect various systems in the body, and its management often involves the use of corticosteroids.
Firstly, it is important to note that the use of corticosteroids by the father does not directly affect the genetic makeup of the sperm. The primary concern regarding medications and potential teratogenic effects (the ability to cause birth defects) usually pertains to the mother’s exposure during pregnancy. In this case, the father’s use of steroids, even at a daily dosage of 1-2 pills for an extended period, is not associated with an increased risk of birth defects in the offspring. Research indicates that paternal health conditions, including autoimmune diseases like SLE, do not significantly increase the risk of congenital anomalies in children.

Regarding the X-ray exposure, the amount of radiation from a couple of X-ray examinations is generally considered low and is unlikely to pose a risk to the developing fetus. The critical period for teratogenic effects is during the first trimester when the organs are forming. Since the father’s X-ray exposure occurred prior to conception, it would not impact the embryo.

As for the use of pain relievers and cold medications, most over-the-counter medications, when used as directed, do not pose a significant risk of causing birth defects. However, it is always advisable for expectant mothers to consult with their healthcare providers regarding any medications taken by either parent during the conception period.

In summary, the father’s SLE and steroid use, along with the X-ray exposure and use of common medications, are not likely to result in congenital anomalies or affect the baby’s health adversely. It is crucial for both parents to maintain open communication with their healthcare providers to ensure a healthy pregnancy and address any concerns that may arise during this period.

In addition to the above, it is worth mentioning that managing SLE effectively is important for the father’s health and can indirectly benefit the family. Stress management, regular medical check-ups, and adherence to prescribed treatments can help in maintaining overall well-being. If the father is planning to conceive, it may also be beneficial to discuss with a healthcare provider about optimizing his health and any necessary adjustments to his medication regimen to ensure the best possible outcomes for both parents and the baby.
In conclusion, while the father's health and medication use are important considerations, they do not significantly increase the risk of birth defects. The focus should remain on ensuring that both parents are in good health and that any medications are used appropriately under medical guidance.

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