Your Health Check Report: Key Lab Results Explained - Family Medicine

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Health Check Report


Hello, I completed my health check report at work.
Overall, it's okay, but I don't understand some of the indices.
Urinalysis: leukocyte esterase (+++); liver function tests: alkaline phosphatase (30), gamma-glutamyl transferase (35), lactate dehydrogenase (183).
Please let me know what these mean.
All other tests are normal.

Xiao Hua, 30~39 year old female. Ask Date: 2005/07/06

Dr. Lin Mingxing reply Family Medicine


To the Laboratory Department of Tainan Hospital, Department of Health, Executive Yuan:
Hello,
Regarding the questions you raised, here are the brief responses:
Urinalysis: The presence of leukocyte esterase (+++) indicates a test for the presence of white blood cells in the urine.
This test utilizes the reaction between the granular leukocyte's contained esterase and the chemicals on the test strip to determine if white blood cells are present in the urine.
The (+++) signifies the intensity of this substance.
Normal urine typically shows a negative reaction.
Liver function tests: Alkaline phosphatase in healthy individuals primarily originates from the liver and bones, with our hospital's normal reference range being 30-88 IU/L for alkaline phosphatase measurement.
This test is mainly used for diagnosing liver, biliary, and skeletal system diseases and serves as an indicator of extrahepatic biliary obstruction and liver function status.
Physiological elevation: In children during their physiological skeletal development phase, alkaline phosphatase activity can be 1 to 2 times higher than that of normal individuals.
Gamma-glutamyl transferase (GGT): This enzyme is primarily used for diagnosing liver damage due to alcohol intoxication, with our hospital's normal reference range being 0-52 IU/L.
Lactate dehydrogenase (LDH): Serum lactate dehydrogenase measurement is a clinical laboratory test, with the specimen being venous serum.
Our hospital's normal reference range is 260-480 IU/L.
Elevated levels are commonly seen in malignancies, leukemia, myocardial infarction, renal disease, hepatitis, cirrhosis, obstructive jaundice, hemolytic anemia, megaloblastic anemia, muscle injury, and progressive muscular atrophy.
Tainan Hospital wishes you good health and all the best!

Reply Date: 2005/07/06

More Info


Understanding your health check report is crucial for maintaining your overall well-being. Based on the lab results you've provided, let's break down the key components, particularly focusing on the urine test results and liver function tests.


Urine Test Results
1. Leukocyte Esterase (+++):
- The presence of leukocyte esterase in urine indicates that there may be white blood cells (WBCs) present, which often suggests an infection or inflammation in the urinary tract. A result of (+++) indicates a significant presence of this enzyme, which typically correlates with a urinary tract infection (UTI). It is advisable to follow up with a urine culture to identify the specific bacteria causing the infection and to determine the appropriate antibiotic treatment.


Liver Function Tests
1. Alkaline Phosphatase (30 U/L):
- Alkaline phosphatase (ALP) is an enzyme found in various tissues throughout the body, with the highest concentrations in the liver, bones, kidneys, and bile ducts. Normal levels can vary, but typically, values between 44 to 147 U/L are considered normal for adults. A result of 30 U/L is below the normal range, which may suggest a few possibilities, including malnutrition or a deficiency in certain vitamins and minerals. It’s important to discuss this result with your healthcare provider to determine if further investigation is needed.

2. Gamma-Glutamyl Transferase (GGT) (35 U/L):
- GGT is another enzyme that is primarily found in the liver. It plays a role in the metabolism of glutathione and the transport of amino acids across cell membranes. Normal GGT levels typically range from 9 to 48 U/L. A result of 35 U/L falls within the normal range, which is a positive sign indicating that there is likely no significant liver damage or disease at this time.

3. Lactate Dehydrogenase (LDH) (183 U/L):
- LDH is an enzyme found in almost all body tissues, and it is released during tissue damage. Normal LDH levels typically range from 140 to 280 U/L. A result of 183 U/L is within the normal range, suggesting that there is no acute tissue damage or significant underlying disease affecting the tissues being monitored.


Summary and Recommendations
- Leukocyte Esterase: The significant presence of leukocyte esterase suggests a potential urinary tract infection. It is advisable to consult with your healthcare provider for further testing, such as a urine culture, to confirm the diagnosis and determine the appropriate treatment.


- Liver Function Tests: Your alkaline phosphatase is slightly low, while GGT and LDH are within normal ranges. While the low ALP could indicate nutritional deficiencies, it is essential to discuss these results with your healthcare provider to rule out any underlying issues and to ensure that your liver function is being adequately monitored.


General Advice
- Follow-Up: It is crucial to follow up on any abnormal results with your healthcare provider. They may recommend additional tests or lifestyle changes based on your overall health status and medical history.


- Lifestyle Considerations: Maintaining a balanced diet, staying hydrated, and engaging in regular physical activity can significantly impact your overall health and help prevent future health issues.

- Regular Check-Ups: Regular health check-ups are vital for early detection and management of potential health problems. Ensure that you keep up with routine screenings and lab tests as recommended by your healthcare provider.

In conclusion, while some of your results are within normal ranges, the presence of leukocyte esterase warrants further investigation. Always consult with your healthcare provider for personalized advice and treatment options based on your specific health needs.

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