Dialysis Access and Its Impact on Ventricular Hypertrophy - Cardiology

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The issue of dialysis access and ventricular hypertrophy?


I am a patient who is about to undergo dialysis.
After having a fistula surgery on my right arm, I have been experiencing occasional sharp pains in my left chest.
I need to hold my breath and take deep breaths for relief.
After going to the hospital for an electrocardiogram, it was found that I have left ventricular hypertrophy.
This is believed to be caused by excessive blood flow from the fistula to the heart, leading to obstruction and difficulty in blood ejection.
To alleviate this symptom, is it possible to reduce the size of the fistula? This is what the doctor suggested; is this correct? Currently, I am taking one aspirin daily and half a tablet of Acedo three times a day.
Is this medication regimen appropriate? This is my main concern.
Thank you for taking the time to respond to my question!

Mìsī Fótuó, 30~39 year old female. Ask Date: 2005/08/26

Dr. Chen Guifeng reply Cardiology


Occasional sharp pain in the left chest can sometimes be caused by nerve or muscle inflammation.
An electrocardiogram showing left ventricular hypertrophy may not be definitive, and further evaluation with additional tests such as a chest X-ray or echocardiogram is necessary to confirm the diagnosis.
Thank you for your inquiry.

Reply Date: 2005/08/26

More Info


Dialysis access, particularly through arteriovenous (AV) fistulas or grafts, is a critical aspect of managing patients with end-stage renal disease (ESRD) requiring hemodialysis. Understanding the implications of dialysis access on cardiovascular health, particularly ventricular hypertrophy, is essential for patients undergoing this treatment.

Ventricular hypertrophy (VH) refers to the thickening of the heart's ventricular walls, which can occur due to various factors, including increased workload on the heart. In patients with chronic kidney disease (CKD) or those on dialysis, several mechanisms contribute to the development of VH. One significant factor is volume overload, which can result from fluid retention due to impaired kidney function. When the kidneys are unable to excrete excess fluid, the heart must pump harder to accommodate the increased blood volume, leading to hypertrophy.

In your case, the left ventricular hypertrophy (LVH) observed on your electrocardiogram (ECG) may be related to the increased blood flow and pressure resulting from the AV fistula created for dialysis access. The fistula allows for a high flow of blood, which can increase the workload on the heart, especially if there is an underlying condition such as hypertension or if the heart is already compromised. This increased flow can lead to a compensatory response from the heart, resulting in hypertrophy.

Regarding your symptoms of chest pain and the need to alter your breathing to alleviate discomfort, these could be related to the increased cardiac workload and the resultant LVH. It is crucial to address these symptoms with your healthcare provider, as they may indicate that your heart is struggling to cope with the increased demands placed on it.

As for the suggestion of narrowing the fistula, this is a complex decision that should be made by your nephrologist and vascular surgeon. While reducing the flow through the fistula may alleviate some of the symptoms associated with LVH, it could also compromise the effectiveness of dialysis. The goal is to maintain adequate dialysis access while managing any cardiovascular complications. Therefore, any adjustments to the fistula should be carefully considered and monitored.

Regarding your medication regimen, the use of aspirin is common in patients with cardiovascular concerns, as it helps reduce the risk of thrombotic events. The use of Amlodipine (the "愛速得錠" you mentioned) is also appropriate for managing hypertension, which is crucial in preventing further cardiac complications. However, the specific dosages and combinations of medications should always be tailored to your individual health needs and monitored by your healthcare provider.

In summary, the relationship between dialysis access and ventricular hypertrophy is multifaceted, involving hemodynamic changes and fluid management. It is essential to work closely with your healthcare team to monitor your heart health, manage your symptoms, and adjust your treatment plan as necessary. Regular follow-ups, medication adherence, and lifestyle modifications can significantly impact your overall cardiovascular health while undergoing dialysis. Always communicate openly with your healthcare providers about any new or worsening symptoms, as early intervention can lead to better outcomes.

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