Managing Acne with Isotretinoin: Common Concerns and Tips - Dermatology

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Isotretinoin


Hello Dr.
Jiang, I am currently a freshman.
Since my senior year in high school, I have been experiencing persistent acne on my cheeks.
I once saw a doctor who prescribed me tetracycline, which was very effective at first, but after the acne cleared up, I stopped taking it.
About a month ago, I visited Dr.
Lin Bing-Huang, who prescribed oral isotretinoin for me.
However, I have been experiencing continuous breakouts.
Since I swim every day, I sometimes feel that swimming might be worsening my acne.
Is that possible?
I am currently using topical isotretinoin, and my skin is very dry, but the acne continues to increase and is even red and swollen.
I am afraid of getting dark spots, so I use sunscreen.
Are there any brands of sunscreen that are truly non-comedogenic? Dr.
Lin said it was okay to use, but he is a bit stern, so I hesitate to ask him.

I have been on the medication for almost a month now.
Is it normal for the acne to be red and swollen? If it is red and swollen, can I continue using isotretinoin? Medical literature states that isotretinoin is more irritating than alpha hydroxy acids, but I feel that glycolic acid seems to be more irritating than isotretinoin.
Thank you for patiently reading my questions.
May Jesus grant you peace.

Best regards,
Huai-En

Huai En, 10~19 year old female. Ask Date: 2005/08/29

Dr. Jiang Zheen reply Dermatology


Oral isotretinoin can sometimes cause an initial worsening of acne during the first month of treatment for some individuals.
I believe you can stop using your topical retinoids.
Dr.
Lin Bing-Huang is my senior, and it would be better for you to write down your questions and show them to him, as he has many patients and limited time.
He is actually a very knowledgeable and down-to-earth physician, and you can trust him.
As for sunscreen, any non-oily formulation should be fine to use.
Swimming can sometimes exacerbate your acne.
While on oral isotretinoin, your skin may become very dry, so it is not advisable to apply high concentrations of alpha hydroxy acids.
Treating acne requires patience and collaboration with your physician, and the vast majority of patients experience good results.
Wishing you peace, and Jesus loves you.

Reply Date: 2005/08/29

More Info


Managing acne can be a challenging journey, especially when considering treatments like isotretinoin (commonly referred to as A酸 or Accutane). It’s important to understand both the benefits and potential side effects of this medication, as well as how to manage your skin during treatment.

First, isotretinoin is a powerful retinoid that is often prescribed for severe acne that has not responded to other treatments. It works by reducing the size and activity of sebaceous (oil) glands, decreasing oil production, and promoting skin cell turnover. While many patients experience significant improvement, it is not uncommon for acne to worsen initially during the first few weeks of treatment. This is sometimes referred to as an "initial breakout," and it can be disheartening. However, it is usually a temporary phase, and many patients see improvement after this period.

Regarding your experience with swimming, it is possible that chlorine in pool water can irritate the skin, especially when combined with the drying effects of isotretinoin. If you notice that swimming exacerbates your acne, consider reducing the frequency or duration of your swims, or ensure you rinse your face thoroughly afterward to remove any chlorine residue.

Dryness is a common side effect of isotretinoin, and it’s crucial to manage this effectively. Using a gentle, non-comedogenic moisturizer can help alleviate dryness without clogging pores. Look for products labeled as "oil-free" or "non-acnegenic." Additionally, using a gentle cleanser that does not strip the skin of its natural oils can also be beneficial.

When it comes to sunscreen, it is essential to protect your skin from UV damage, especially while on isotretinoin, as the medication can increase photosensitivity. Look for broad-spectrum sunscreens with an SPF of 30 or higher that are labeled as non-comedogenic. Some reputable brands that are often recommended for acne-prone skin include Neutrogena, La Roche-Posay, and EltaMD. Always check the ingredient list to ensure there are no known acne-triggering components.

As for the redness and swelling you are experiencing, it is not uncommon for isotretinoin to cause some degree of irritation, especially in the early stages. However, if the redness and swelling are severe or worsening, it’s important to consult your dermatologist. They may recommend adjusting your dosage or suggest additional treatments to help manage these side effects.

Regarding your comparison between isotretinoin and glycolic acid (果酸), it’s important to note that while both are exfoliants, they work differently. Glycolic acid is an alpha hydroxy acid (AHA) that primarily helps with surface exfoliation, while isotretinoin affects deeper layers of the skin and oil production. Some individuals may find glycolic acid irritating, especially if their skin is already sensitive or compromised, which could explain your experience.
In summary, managing acne with isotretinoin requires patience and careful skincare. Monitor your skin’s response, maintain open communication with your dermatologist, and do not hesitate to ask questions or express concerns during your appointments. Your skin's health is paramount, and adjustments can often be made to ensure the best possible outcome. Remember, the journey to clear skin can take time, but with the right approach, improvement is achievable.

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