Hepatitis B: Key Concerns and Precautions - Gastroenterology and Hepatology

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Hepatitis B-related issues~ urgent


Hello, I would like to ask about my boyfriend who has hepatitis B.
His school health check results are as follows: HBsAg+++(abnormal), Anti-HBs(-), HBeAg(-), Anti-HCV(-).
Is this serious? What should we pay attention to? Is it still effective to get vaccinated? Thank you!

Fan Nao, 20~29 year old female. Ask Date: 2005/09/29

Dr. Chen Jianhong reply Gastroenterology and Hepatology


Hello! Your boyfriend's report only confirms that he has been infected with Hepatitis B, but the severity of the infection requires further detailed examination.
It is recommended that your boyfriend visit a hepatobiliary specialist for additional testing.
Since he has been infected with Hepatitis B, he cannot receive the vaccine anymore, as there will be no immune response.
What he needs is regular follow-up appointments with a hepatobiliary specialist.
For detailed information about Hepatitis B, you can always refer to the Taiwan e-Hospital website.

Reply Date: 2005/09/29

More Info


Hepatitis B is a significant public health concern, particularly in regions where the virus is endemic. Understanding the implications of your boyfriend's test results is crucial for managing his health and preventing transmission. Let's break down the results and address your concerns.

1. Understanding the Test Results:
- HBsAg (Hepatitis B Surface Antigen): A positive result (HBsAg+++) indicates that your boyfriend is currently infected with the Hepatitis B virus (HBV). This means that the virus is actively replicating in his body.

- Anti-HBs (Hepatitis B Surface Antibody): A negative result indicates that he has not developed immunity to the virus, either through vaccination or recovery from a past infection.

- HBeAg (Hepatitis B e Antigen): A negative result suggests that he may have a lower level of viral replication, which is often associated with a less aggressive form of the infection. However, it does not mean that he is free from the virus.

- Anti-HCV (Hepatitis C Antibody): A negative result indicates that he is not infected with Hepatitis C, which is a separate virus.

2. Severity of the Condition:
- The presence of HBsAg indicates an active infection, which can lead to acute or chronic liver disease. The severity of the infection can vary widely. Some individuals may experience mild symptoms, while others may develop severe liver damage, cirrhosis, or liver cancer over time.

- It is essential for your boyfriend to have regular follow-ups with a healthcare provider to monitor liver function and assess the risk of complications.

3. Precautions:
- Avoid Transmission: Hepatitis B is transmitted through blood and bodily fluids. It is crucial to avoid sharing personal items such as razors, toothbrushes, or needles. Safe sex practices should be employed to prevent sexual transmission.

- Vaccination: Since your boyfriend is already infected, receiving the Hepatitis B vaccine will not be effective for him. However, it is essential for close contacts, including you, to be vaccinated to prevent future infections. The vaccine is highly effective and can provide immunity against the virus.

- Regular Monitoring: He should have regular check-ups, including liver function tests and possibly imaging studies, to monitor the health of his liver and the status of the infection.

4. Treatment Options:
- Depending on the severity of the infection and liver function, antiviral medications may be considered. These can help to suppress the virus and reduce the risk of liver damage. Common antiviral medications include tenofovir and entecavir.

- Lifestyle modifications, such as maintaining a healthy diet, avoiding alcohol, and managing weight, can also support liver health.

5. Long-term Outlook:
- Many individuals with Hepatitis B can live long and healthy lives with proper management. Some may clear the virus spontaneously, while others may require ongoing treatment. The key is to stay informed and proactive about health management.

In summary, your boyfriend's condition requires careful monitoring and management. It is essential for him to work closely with a healthcare provider to determine the best course of action. Additionally, you should consider getting vaccinated against Hepatitis B to protect yourself. Regular follow-ups and lifestyle adjustments can significantly impact his health outcomes and quality of life.

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