Abnormalities in complete blood count (CBC) results?
Hello Dr.
Tang,
I have some questions I would like to ask you regarding my boyfriend's recent health check-up results.
In the complete blood count, there are several abnormal values highlighted in red: WBC 5.62, RBC 6.52 (elevated), HB 12.3 (low), HT 40.1, MCV 61.52 (low), MCH 18.92 (low), MCHC 30.72 (low), and PLT 267.
Could you please help me with the following:
1.
What type of anemia does this indicate? It seems that several values suggest thalassemia, but I have read that in thalassemia, the RBC count is typically low, whereas my boyfriend's RBC is elevated.
I would appreciate your interpretation.
2.
Should he reduce the intake of iron-rich foods in his diet?
3.
Additionally, do the blood glucose level of 67 and GPT of 64 have any relation to the anemia?
Thank you very much for taking the time to respond amidst your busy schedule.
I am very grateful!
Bàng bàng táng, 20~29 year old female. Ask Date: 2005/10/26
Dr. Tang Jieru reply Cardiology
Hello, Lollipop: In this data, the only meaningful comparison is MCV=61.52 (<80); other values such as RBC, MCH, and MCHC have high variability and may not necessarily have clinical significance.
An MCV <80 could indicate either thalassemia or iron deficiency anemia, but this blood test alone cannot definitively distinguish between the two.
It is recommended to have tests for ferritin, iron/TIBC, and hemoglobin electrophoresis at the hospital for proper differentiation.
Only in the case of iron deficiency anemia is it necessary to consume iron-rich foods; until a diagnosis is confirmed, there is no need to deliberately increase iron intake.
If he is ultimately diagnosed with thalassemia and you are planning to marry him, remember that you should also get tested.
If both partners have thalassemia, there is a 25% chance that the child could develop severe thalassemia, which would require lifelong blood transfusions.
Your boyfriend's blood sugar levels are normal, but his liver enzymes are elevated.
Does he drink alcohol frequently? Does he stay up late? Has he been tested for hepatitis B or C? If necessary, an ultrasound examination of the liver should also be performed to check for abnormalities.
Thank you for your inquiry.
Reply Date: 2005/10/26
More Info
Understanding abnormal blood test results can be quite complex, especially when multiple parameters are involved. Based on the blood test results you provided, let's break down the findings and address your questions regarding anemia and other related concerns.
1. Type of Anemia: The results indicate a high RBC count (6.52), but low hemoglobin (HB 12.3), low hematocrit (HT 40.1), and low MCV (61.52), MCH (18.92), and MCHC (30.72). These findings suggest a microcytic anemia, which is often associated with iron deficiency or thalassemia. In thalassemia, you might see a normal or elevated RBC count, but the hemoglobin levels are typically low, and the red blood cells are smaller than normal (microcytic). The elevated RBC count in your boyfriend's case could indicate a compensatory response to low hemoglobin levels, which is not uncommon in certain types of anemia, including thalassemia. Therefore, while the RBC count is high, the other parameters suggest that this is not typical of a standard iron deficiency anemia, which usually presents with low RBC, low hemoglobin, and low hematocrit.
2. Dietary Considerations: If the anemia is indeed due to iron deficiency, increasing iron intake through diet would be beneficial. However, if thalassemia is suspected, the approach is different. In thalassemia, excessive iron intake can lead to iron overload, which can be harmful. Therefore, it is crucial to determine the exact type of anemia before making dietary changes. Consulting with a healthcare provider or a dietitian who specializes in hematology would be advisable to tailor dietary recommendations based on the specific diagnosis.
3. Blood Sugar and GPT Levels: The blood glucose level of 67 mg/dL is on the lower end of the normal range, but it is not directly related to anemia. It’s essential to consider the context of this reading, such as whether it was taken fasting or after a meal. The GPT (ALT) level of 64 is slightly elevated, which may indicate liver function issues, but it is not typically associated with anemia. Elevated liver enzymes can arise from various conditions, including fatty liver disease, alcohol consumption, or medication effects. It would be prudent to follow up on these results with a healthcare professional to assess liver function further and determine if any additional tests are necessary.
In summary, your boyfriend's blood test results suggest a form of microcytic anemia, possibly thalassemia, given the elevated RBC count alongside low hemoglobin and other indices. It is crucial to consult with a healthcare provider for further evaluation, including possibly a hemoglobin electrophoresis test to confirm the diagnosis. Dietary recommendations should be tailored based on the specific type of anemia diagnosed. Additionally, the blood sugar and liver enzyme levels should be monitored and discussed with a healthcare professional to rule out any underlying conditions. Regular follow-up and comprehensive evaluation are key to managing these health concerns effectively.
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