Does Testosterone Injection Cause Hair Loss? the Risks - Dermatology

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Does injecting male hormones cause hair loss?


Because I am a transsexual, I want to inject male hormones, but I have heard that excessive male hormones can lead to hair loss.
How can I determine my likelihood of experiencing hair loss? Is there a way to check for this?

Mao, 10~19 year old female. Ask Date: 2005/11/12

Dr. Zheng Lizhen reply Dermatology


Hello: Currently, there is no method of examination that can determine the probability of hair loss for each individual.
Sincerely, Dr.
Cheng Li-Chen, Dermatologist.

Reply Date: 2005/11/12

More Info


Testosterone injections, particularly those like Sustanon, can indeed have an impact on hair loss, especially in individuals who are genetically predisposed to androgenetic alopecia, commonly known as male pattern baldness. This condition is influenced by the presence of dihydrotestosterone (DHT), a potent derivative of testosterone that binds to hair follicles, leading to their miniaturization and eventual hair loss.

When considering testosterone therapy, it’s essential to understand the risks involved. The likelihood of experiencing hair loss as a side effect of testosterone injections largely depends on your genetic background. If you have a family history of male pattern baldness, your risk of experiencing hair loss may be higher. Unfortunately, there is no definitive test to predict whether you will experience hair loss from testosterone therapy; however, a consultation with a healthcare provider can help assess your risk based on family history and other factors.

In terms of monitoring, some individuals may choose to undergo a scalp examination or a hair density test to evaluate the health of their hair follicles before starting testosterone therapy. This can provide a baseline to compare against after treatment begins. Additionally, dermatologists can perform a hair pull test or a scalp biopsy if necessary to assess the condition of the hair follicles.

It’s also important to consider the dosage and duration of testosterone therapy. Higher doses and prolonged use may increase the risk of hair loss. Therefore, it’s crucial to follow your healthcare provider's recommendations regarding dosage and frequency of injections. Regular follow-ups can help monitor any side effects, including hair loss.

If you are concerned about hair loss but still wish to pursue testosterone therapy, there are potential strategies to mitigate this risk. Medications like finasteride, which inhibit the conversion of testosterone to DHT, may be prescribed alongside testosterone therapy to help protect against hair loss. However, finasteride comes with its own set of potential side effects, including sexual dysfunction, so it’s essential to discuss these options thoroughly with your healthcare provider.

In summary, while testosterone injections can lead to hair loss, particularly in those predisposed to male pattern baldness, the extent of this risk varies among individuals. Consulting with a healthcare professional who specializes in hormone therapy can provide personalized guidance and help you weigh the benefits and risks of treatment. Regular monitoring and open communication with your provider can also help manage any side effects that may arise during therapy.

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