Hair Loss in Lupus Patients: Causes and Treatments - Internal Medicine

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Systemic lupus erythematosus (SLE)


Hello, doctor.
I have a friend who is only 28 years old and has been diagnosed with lupus erythematosus.
She is also undergoing dialysis.
Recently, I noticed that she has some bald patches on her scalp.
Is this normal? Could it be related to stress? Will this hair loss continue? Is there any medication that can help? How can we prevent her condition from worsening? It's really difficult to find a kidney donor, and I feel so sorry for her.
Could you please help me with these questions? Thank you!

vivi, 20~29 year old female. Ask Date: 2005/12/21

Dr. Chen Baoli reply Internal Medicine


Hello VIVI: Regarding the issue of hair loss, it involves different types and quantities of hair loss, each with various causes and outcomes.
It may be related to stress, nutrition, medications, or even the underlying disease itself.
If it is related to the disease, it indicates that the disease activity is still active, and proper medication management is essential.
Whether hair will regrow depends on whether the patient is a typical case of systemic lupus erythematosus (SLE) or has discoid lupus erythematosus (skin manifestations).
In the latter case, the chances of regrowth are lower, but it is not entirely impossible.
Therefore, it is recommended that she consult her attending physician for treatment.
Additionally, patients with lupus nephritis who are on dialysis face significant challenges, and they require support and encouragement from family and friends.
It is heartening to know that you care for her well-being.
As long as she adheres to her medication and treatment while avoiding triggers, I believe she can lead a happy and confident life.
Wishing you health and happiness, Chen Baoli, Changhua Hospital, concerned about your health.

Reply Date: 2005/12/21

More Info


Hair loss in patients with systemic lupus erythematosus (SLE), commonly known as lupus, can be a distressing symptom that affects both physical appearance and emotional well-being. Understanding the causes and potential treatments for hair loss in lupus patients is crucial for managing this condition effectively.


Causes of Hair Loss in Lupus Patients
1. Disease Activity: Hair loss in lupus patients can be associated with the activity of the disease itself. When lupus is active, it can lead to inflammation that affects the hair follicles, resulting in hair thinning or patches of hair loss. This condition is often referred to as "lupus hair loss" and can manifest as diffuse thinning or localized patches.

2. Medications: Many lupus patients are treated with corticosteroids and immunosuppressive drugs to manage their symptoms. While these medications can be effective in controlling lupus, they may also have side effects, including hair loss. For instance, corticosteroids can lead to telogen effluvium, a temporary form of hair loss that occurs after a significant stressor or change in the body.

3. Stress: Living with a chronic illness like lupus can be incredibly stressful, and stress itself is a known factor that can contribute to hair loss. Emotional and physical stress can trigger conditions like telogen effluvium, where hair follicles prematurely enter the resting phase, leading to increased shedding.

4. Nutritional Deficiencies: Lupus patients may experience nutritional deficiencies due to dietary restrictions or malabsorption issues. Deficiencies in essential nutrients, such as iron, zinc, and vitamins, can contribute to hair loss.

5. Other Autoimmune Conditions: Lupus patients may also have other autoimmune conditions that can cause hair loss, such as alopecia areata, which leads to patchy hair loss.


Treatment Options
1. Medical Management: The first step in addressing hair loss is to ensure that the underlying lupus is well-controlled. This may involve adjusting medications or dosages under the guidance of a healthcare provider. If medications are contributing to hair loss, discussing alternatives with a doctor is essential.

2. Topical Treatments: Minoxidil is a topical treatment that can stimulate hair growth and is often used for various types of hair loss. It may be beneficial for lupus patients experiencing hair thinning.

3. Nutritional Support: Ensuring a well-balanced diet rich in vitamins and minerals can help support hair health. Consulting with a nutritionist may be beneficial to address any deficiencies.

4. Stress Management: Techniques such as mindfulness, yoga, and counseling can help manage stress levels, which may, in turn, reduce hair loss related to stress.

5. Supportive Care: Emotional support from friends and family can be invaluable. Encouraging your friend to join support groups or connect with others who have lupus can provide comfort and understanding.


Prognosis
The prognosis for hair regrowth in lupus patients varies. If the hair loss is due to active disease, controlling the lupus may lead to regrowth. However, if the hair loss is related to scarring from lupus lesions or other irreversible factors, regrowth may be limited. It is essential for your friend to maintain regular follow-ups with her healthcare provider to monitor her lupus and adjust treatment as necessary.

In conclusion, hair loss in lupus patients can result from a combination of disease activity, medication side effects, stress, and nutritional factors. A comprehensive approach that includes medical management, nutritional support, and stress reduction can help address this issue. Encouraging your friend to seek professional advice and support will be crucial in managing her condition and improving her quality of life.

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