Prolactin Levels and Long-Term Effects of Parlodel - Obstetrics and Gynecology

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Hello CHO,
Thank you for your inquiry regarding your prolactin levels and the long-term effects of Parlodel (bromocriptine). I understand your concerns, and I will address both of your questions in detail.

1. Prolactin Levels and Response to Parlodel: It is not uncommon for prolactin levels to fluctuate, even when a medication like Parlodel is being taken. Prolactin is a hormone produced by the pituitary gland, and its levels can be influenced by various factors, including stress, time of day, and even the method of blood collection. The initial level of 34 ng/mL and the subsequent rise to 49 ng/mL after five months of treatment could be attributed to several factors. First, the dosage of Parlodel may not have been sufficient to suppress prolactin production effectively. While you started with half a tablet daily, your doctor has now increased the dosage to one tablet daily, which is a common adjustment when the initial treatment does not yield the desired results. Additionally, the underlying cause of elevated prolactin levels, such as a prolactinoma (a benign pituitary tumor), may require more aggressive treatment or monitoring. It is essential to have regular follow-ups with your healthcare provider to assess the effectiveness of the treatment and make necessary adjustments.

2. Long-Term Use of Parlodel and Potential Side Effects: Parlodel is generally well-tolerated, but like any medication, it can have side effects, especially with long-term use. Common side effects include nausea, dizziness, headaches, and gastrointestinal disturbances. In some cases, patients may experience more severe effects such as orthostatic hypotension (a drop in blood pressure when standing), which can lead to dizziness or fainting. While long-term use of Parlodel is often necessary for managing conditions like hyperprolactinemia, it is crucial to monitor for any adverse effects.
Regarding your concern about long-term side effects or "aftereffects," it is important to note that while some patients may experience side effects, many do not. The risk of developing significant complications is generally low, especially when the medication is taken as prescribed and under the supervision of a healthcare provider. However, if you experience any unusual symptoms or side effects, it is essential to communicate these to your doctor promptly.

In summary, the increase in your prolactin levels could be due to various factors, including dosage adjustments and the underlying condition being treated. Long-term use of Parlodel is typically safe, but regular monitoring and communication with your healthcare provider are key to managing your treatment effectively. If you have further concerns or experience any side effects, please do not hesitate to reach out to your healthcare provider for personalized advice.

Best wishes for your health,
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