Are There Side Effects of Ketoprofen for Arthritis and Pain Relief?

I would like to know if this ingredient has any side effects?

Hello, doctor! ^^~ Does this medication have any side effects on the human body? Could it cause harm to the body? Below are its ingredients and indications: Indications: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, lower back pain, and ingredients: KETOPROFEN.
Thank you, I appreciate it!

Jia Win, 20~29 year old female. Ask Date: 2006/03/10

Dr. Liao Lingmei reply Pharmacology

Dear Jia Win,
Ketoprofen is classified pharmacologically as a non-steroidal anti-inflammatory drug (NSAID) and is commonly used; however, it should be considered a prescription medication and is not suitable for long-term use without a physician's prescription.
All medications have potential side effects, which may not manifest in every individual.
Each person may experience slightly different side effects (reactions) due to their unique physiology.
If you have previously experienced allergic reactions (such as skin inflammation or edema) from pain relievers, it is not advisable to use this medication.
Patients with asthma or allergic conditions should exercise caution when taking this drug.
It can cause gastrointestinal discomfort, particularly in the elderly, and may also have implications for individuals with cardiovascular diseases and pregnant women.

Please heed your pharmacist's advice and refrain from using prescription medications long-term without a physician's guidance.
Having a proper source for your medications can also provide more accurate information.
Wishing you health and happiness.

Reply Date: 2006/03/10

More Info

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used to relieve pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, and other musculoskeletal disorders. While it can be effective for managing pain and inflammation, it is essential to understand that, like all medications, ketoprofen can have side effects and potential risks.

Common Side Effects
The most frequently reported side effects of ketoprofen include:
1. Gastrointestinal Issues: NSAIDs, including ketoprofen, can irritate the gastrointestinal tract, leading to symptoms such as stomach pain, heartburn, nausea, vomiting, and diarrhea. In some cases, they can cause more severe complications like ulcers or gastrointestinal bleeding, especially in older adults or those with a history of gastrointestinal problems.

2. Kidney Effects: Long-term use of ketoprofen can affect kidney function. Patients with pre-existing kidney conditions or those who are dehydrated are at a higher risk of experiencing kidney-related side effects.

3. Cardiovascular Risks: There is an increased risk of cardiovascular events, such as heart attack or stroke, associated with the use of NSAIDs, particularly in patients with existing heart conditions or risk factors.

4. Allergic Reactions: Some individuals may experience allergic reactions to ketoprofen, which can manifest as skin rashes, itching, swelling, or difficulty breathing. If any of these symptoms occur, it is crucial to seek medical attention immediately.

5. Liver Effects: Although rare, ketoprofen can cause liver damage, which may present as jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.

Special Considerations
- Pre-existing Conditions: Patients with asthma, allergies, or a history of gastrointestinal issues should use ketoprofen with caution. It is advisable to consult a healthcare provider before starting the medication.

- Drug Interactions: Ketoprofen can interact with other medications, including blood thinners (like warfarin), other NSAIDs, and certain antihypertensives, potentially increasing the risk of adverse effects.

- Pregnancy and Breastfeeding: Ketoprofen is generally not recommended during pregnancy, particularly in the third trimester, due to potential risks to the fetus. It is also excreted in breast milk, so nursing mothers should consult their healthcare provider before use.

Conclusion
While ketoprofen can be an effective option for managing pain and inflammation associated with arthritis and other conditions, it is essential to be aware of its potential side effects and risks. Patients should always discuss their medical history and any other medications they are taking with their healthcare provider before starting ketoprofen. Regular monitoring and follow-up can help mitigate risks and ensure the safe use of this medication. If you experience any concerning symptoms while taking ketoprofen, it is crucial to seek medical advice promptly.

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