Mumps: Immunity, Recurrence, and Health Risks in Children - Pediatrics

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Mumps


Is mumps a one-time infection that provides lifelong immunity? A child has been diagnosed with mumps three times by two different physicians from last year to the present.
The doctors suggested that after recovery, if there is another infection of mumps, a blood test should be conducted.
Does this imply that the child is at high risk for lymphatic cancer? What is your assessment or recommendation? Please share your insights.
Thank you!

asser, 30~39 year old female. Ask Date: 2006/06/20

Dr. Hong Shuokun reply Pediatrics


Hello! Parotitis, theoretically, provides lifelong immunity after one infection.
The MMR (measles, mumps, rubella) vaccine was administered at 15 months of age, but the efficacy is not 100%, and antibody levels can decrease with age, which may lead to reinfection.
However, recurrent parotitis is a different issue and should be evaluated for sialolithiasis, xerostomia/Sjögren's syndrome, or benign recurrent parotitis of childhood.
Salivary gland imaging and salivary secretion tests are necessary for diagnosis.
Recurrent parotitis is not related to lymphatic cancer.

Reply Date: 2006/06/20

More Info


Mumps, a viral infection caused by the mumps virus, is known for causing swelling of the salivary glands, particularly the parotid glands. Traditionally, it was believed that once a person contracted mumps, they would develop lifelong immunity. However, recent observations have indicated that reinfections can occur, albeit infrequently. This raises questions about the nature of immunity and the potential health risks associated with multiple infections.

In the case of your child, experiencing mumps three times is unusual, as most children typically acquire immunity after a single infection. The mumps virus generally elicits a robust immune response, leading to the production of antibodies that provide protection against future infections. However, there are instances where individuals may not develop adequate immunity after the initial infection, or they may have a weakened immune response due to other underlying health conditions.

The recommendation for blood tests following your child's recovery from mumps is prudent. These tests can help determine the presence of specific antibodies against the mumps virus, which can clarify whether your child has developed immunity or if there are other underlying issues affecting their immune system.
Regarding the concern about lymphatic cancer (lymphoma), it is essential to note that while recurrent infections can sometimes indicate an underlying immunodeficiency, they do not directly correlate with an increased risk of lymphoma. Lymphoma is a type of cancer that originates in the lymphatic system, and its development is influenced by various factors, including genetic predisposition, environmental factors, and certain infections.
If your child has been diagnosed with mumps multiple times, it may be worthwhile to consult with a pediatric immunologist or a specialist in infectious diseases. They can conduct a thorough evaluation to assess your child's immune function and determine if there are any underlying conditions that need to be addressed.
In addition to seeking specialized medical advice, it is also crucial to ensure that your child is up to date with vaccinations. The MMR (measles, mumps, rubella) vaccine is highly effective in preventing mumps and is typically administered in two doses during childhood. Vaccination not only protects the individual but also contributes to herd immunity, reducing the overall incidence of mumps in the community.

In summary, while mumps typically provides lifelong immunity after a single infection, recurrent cases can occur and may warrant further investigation. Blood tests can help assess your child's immune status, and consulting with a specialist can provide additional insights into their health. Ensuring that your child is vaccinated is also a critical step in preventing future infections.

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