Can Allergy Immunotherapy Be Used for Treating Atopic Dermatitis in Children? - Dermatology

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Can atopic dermatitis be treated with desensitization therapy?


A child has been diagnosed with atopic dermatitis at National Taiwan University Hospital and is currently on medication.
Recently, I heard about the possibility of using "desensitization therapy" for treatment, which involves an injection once a week for six months.
Is this truly effective? I have heard that this "desensitization therapy" is used for asthma, and I am unsure if it can also be used for atopic dermatitis.
Please assist me, thank you.

Ms. Yu, 30~39 year old female. Ask Date: 2006/07/18

Dr. Jiang Yujiao reply Dermatology


Hello: Currently, desensitization therapy is not helpful for atopic dermatitis.
Medication, topical treatments, and skin care are very important for managing atopic dermatitis.
Sincerely, Dr.
Jiang Yu-Jiao, Dermatology.

Reply Date: 2006/07/18

More Info


Allergy immunotherapy, commonly referred to as "desensitization therapy," is primarily used for treating allergic conditions such as allergic rhinitis (hay fever), allergic asthma, and certain insect sting allergies. It involves the gradual exposure of the patient to allergens in order to build up tolerance over time. However, when it comes to atopic dermatitis (AD), also known as eczema, the situation is a bit more complex.

Atopic dermatitis is a chronic inflammatory skin condition characterized by dry, itchy skin and is often associated with other allergic conditions, such as asthma and allergic rhinitis. While there is a strong link between atopic dermatitis and allergies, the use of allergy immunotherapy for treating AD is not as straightforward or widely accepted as it is for other allergic conditions.

Current evidence suggests that allergy immunotherapy may not be effective for all patients with atopic dermatitis. The primary treatment for AD focuses on managing symptoms and preventing flare-ups through a combination of topical treatments (such as corticosteroids and calcineurin inhibitors), moisturizers, and lifestyle modifications. In some cases, systemic medications may be necessary for more severe cases.

Research has shown that while some patients with atopic dermatitis may benefit from allergy immunotherapy, particularly if they have specific IgE-mediated allergies that trigger their eczema, the overall effectiveness of this approach is still under investigation. For example, studies have indicated that immunotherapy may help in cases where environmental allergens, such as pollen or dust mites, are significant triggers for the patient's eczema. However, the response can be variable, and not all patients will experience improvement.

It is also important to note that the treatment of atopic dermatitis should be individualized. Factors such as the patient's age, the severity of the condition, the presence of other allergic diseases, and specific triggers should all be considered when developing a treatment plan. In children, especially, the focus is often on gentle management of symptoms and avoiding known irritants or allergens.

In conclusion, while allergy immunotherapy may have a role in the management of atopic dermatitis for some patients, it is not a standard treatment and should be approached with caution. It is essential to consult with a dermatologist or an allergist who can evaluate the specific circumstances of the child and determine the most appropriate treatment options. The primary goal remains to control the symptoms of atopic dermatitis through established therapies, while considering allergy management as a complementary approach when indicated.

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