How Long Can Hepatitis B Virus Survive Outside the Body? - Internal Medicine

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How long can the hepatitis B virus survive outside the body?


If saliva from a person with highly infectious hepatitis B comes into contact with clothing during a conversation, is there a possibility of transmission to others? How long can the hepatitis B virus survive outside the body? Is it necessary to disinfect objects touched by a person with hepatitis B with 75% alcohol? Will it be effective?

Linlin, 10~19 year old female. Ask Date: 2006/08/12

Dr. Xiao Jingqin reply Internal Medicine


Hello Linlin~~ Hepatitis B virus is transmitted through body fluids, primarily via blood transfusions, sexual contact, sharing needles, and needlestick injuries.
It is not transmitted through respiratory droplets or food.
Hepatitis B is very difficult to survive outside the body; even in standard cell cultures, it is challenging to cultivate.
Once blood dries outside the body, the hepatitis B virus cannot survive.
Although the virus has been found in saliva, semen, and tears, transmission does not occur without "intimate and prolonged" contact (such as sexual intercourse, kissing, or sharing toothbrushes and razors) and if there are no open wounds on the skin or mucous membranes.
Additionally, objects touched by a hepatitis B patient typically do not retain blood or body fluids under normal circumstances, so disinfection is not necessary.
Since 1984, Taiwan has implemented a comprehensive hepatitis B vaccination program, and over 90% of individuals under 22 years old have protective hepatitis B surface antibodies.
Therefore, there is no need for you to be overly concerned.

Reply Date: 2006/08/12

More Info


Hepatitis B virus (HBV) is a significant public health concern, and understanding its survival outside the body is crucial for preventing transmission. The survival of HBV in the external environment is relatively limited compared to other pathogens, but it can still pose a risk under certain conditions.

Research indicates that HBV can survive outside the body for varying periods, depending on environmental factors such as temperature, humidity, and the presence of organic material. Generally, HBV can remain viable on surfaces for at least 7 days, particularly in dried blood. However, once the blood or other bodily fluids containing the virus dry out, the virus's ability to infect diminishes significantly. It is important to note that while HBV can be detected in saliva, the risk of transmission through saliva is much lower than through blood or other body fluids. Close, intimate contact, such as sharing razors or toothbrushes, poses a higher risk of transmission than casual interactions.

If saliva from an individual with high infectivity comes into contact with clothing, the risk of transmission is minimal unless there is a significant amount of saliva and it comes into contact with an open wound or mucous membranes. In general, casual contact, such as talking, does not pose a significant risk for HBV transmission.

Regarding disinfection, using 75% alcohol is effective for disinfecting surfaces that may have been contaminated with HBV. Alcohol solutions of this concentration can effectively inactivate the virus on surfaces, making it a suitable choice for cleaning items that may have come into contact with an infected person's bodily fluids. However, it is essential to ensure that the surface is thoroughly cleaned and that the alcohol remains in contact with the surface for an adequate amount of time to ensure effective disinfection.

In summary, while HBV can survive outside the body for a limited time, the risk of transmission through casual contact is low. Proper hygiene practices, including regular handwashing and disinfecting potentially contaminated surfaces, are effective preventive measures. Vaccination remains the most effective way to prevent HBV infection, and individuals who are unsure of their vaccination status should consider getting vaccinated to protect themselves and others.

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