Gynecomastia in Men: Risks of Breast Cancer and Aging - Breast and Thyroid

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Gynecomastia in males?


Is gynecomastia in males associated with a higher risk of breast cancer? At what age does this condition typically begin to diminish?

Lai, 10~19 year old female. Ask Date: 2006/09/05

Dr. Xie Wenhuai reply Breast and Thyroid


Gynecomastia in males is defined as the presence of tissue beneath the nipple that exceeds two centimeters.
This condition is primarily caused by an imbalance in the secretion of androgens and estrogens in the body.
Gynecomastia can be classified into two types: idiopathic and acquired.
Idiopathic gynecomastia originates during puberty when there is a relative increase in female hormones in males, and it typically resolves gradually over a period of two to three years.
Acquired gynecomastia occurs due to hormonal imbalances caused by diseases or the use of medications, and it is not directly related to breast cancer.

Reply Date: 2006/09/05

More Info


Gynecomastia, the condition characterized by the enlargement of breast tissue in males, is primarily caused by an imbalance between testosterone and estrogen levels in the body. This condition can manifest during different life stages, particularly during puberty and later in life due to various factors such as hormonal changes, medications, or underlying health conditions.

Regarding the risk of breast cancer in men with gynecomastia, it is important to note that while gynecomastia itself is not directly linked to an increased risk of breast cancer, the underlying hormonal imbalances that cause gynecomastia may contribute to a higher risk in certain cases. Men with gynecomastia should be aware that they can develop breast cancer, although it is relatively rare compared to women. The lifetime risk of breast cancer in men is about 1 in 833, which is significantly lower than in women, where the risk is about 1 in 8. However, men with gynecomastia, especially if it is persistent or associated with other risk factors such as family history of breast cancer, genetic mutations (like BRCA2), or other endocrine disorders, may have a slightly elevated risk.

As for the age at which gynecomastia symptoms may resolve, it largely depends on the underlying cause. In adolescent males, gynecomastia often occurs due to hormonal changes during puberty and typically resolves within 6 months to 2 years as hormone levels stabilize. In contrast, gynecomastia that develops later in life, often due to factors such as obesity, liver disease, or certain medications, may not resolve without addressing the underlying cause. In some cases, surgical intervention may be considered if the condition is persistent and causes psychological distress or physical discomfort.

For men experiencing gynecomastia, it is crucial to monitor the condition and seek medical advice if there are any changes, such as an increase in breast size, the presence of a lump, or any unusual symptoms like pain or discharge. Regular follow-ups with a healthcare provider can help ensure that any potential complications, including breast cancer, are detected early.

In summary, while gynecomastia itself does not significantly increase the risk of breast cancer, men with this condition should remain vigilant and consult with healthcare professionals for appropriate evaluation and management. Understanding the nature of gynecomastia, its potential causes, and the importance of monitoring changes can help mitigate risks and promote overall health.

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