Acidic Saliva After Taking Common Medications: A Guide - Family Medicine

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Medication issues


Why do I feel that my saliva tastes sour after taking the following medications for four days: 1.
Psubity/tab 2.
Allegra 180mg 3.
Tidact 150mg 4.
Methylcobalamin 500mcg 5.
Loftyl 150mg? Thank you for your response.

Wenwen, 20~29 year old female. Ask Date: 2006/10/04

Dr. Cai Jueren reply Family Medicine


Hello Wenwen, the symptoms you described are simply side effects of the medication.
They should resolve within a day or two after discontinuing the medication, so there is no need to worry too much.
Thank you for your correspondence, and I hope the above information helps alleviate your concerns.
Dr.
Tsai Jue-ren, Hualien Hospital.

Reply Date: 2006/10/04

More Info


The sensation of acidic saliva after taking certain medications can be attributed to several factors, including the pharmacological properties of the drugs, their effects on the gastrointestinal system, and individual physiological responses. Let's delve into the medications you've mentioned and explore why you might be experiencing this change in saliva acidity.

1. Psubity (likely referring to a medication with a similar name): Depending on its active ingredients, it may influence gastric acid secretion or alter the pH balance in the mouth. Some medications can lead to dry mouth (xerostomia), which can concentrate saliva and alter its perceived acidity.

2. Allegra (Fexofenadine 180mg): This is an antihistamine used primarily for allergic conditions. While it is not typically associated with changes in saliva acidity, antihistamines can cause dry mouth, which may lead to a perception of increased acidity due to reduced saliva flow. Saliva plays a crucial role in neutralizing acids in the mouth, and a decrease in saliva can lead to a more acidic environment.

3. Tidact (likely referring to a medication like Tizanidine): This medication is a muscle relaxant that can also cause dry mouth as a side effect. Similar to Allegra, reduced saliva can lead to a more acidic sensation in the mouth.

4. Methycobal (Methylcobalamin 500mcg): This is a form of vitamin B12 used for nerve health. It is generally well-tolerated and not known to cause changes in saliva acidity. However, individual reactions can vary, and it may interact with other medications you are taking.

5. Loftyl (likely referring to a medication like Lofexidine): This medication is used to manage withdrawal symptoms in opioid dependence. It can also cause dry mouth as a side effect, which may contribute to the sensation of acidic saliva.


Understanding the Mechanism
The mouth's pH can be influenced by various factors, including diet, hydration, and medications. When saliva production decreases, the mouth's natural buffering capacity is compromised, leading to a more acidic environment. This can be exacerbated by the consumption of acidic foods or beverages, which may further alter the pH balance.


Recommendations
1. Hydration: Ensure you are drinking enough water throughout the day. Staying hydrated can help maintain saliva production and mitigate the sensation of acidity.

2. Oral Hygiene: Maintain good oral hygiene practices, including regular brushing and flossing, to help manage any changes in saliva acidity and prevent dental issues.

3. Dietary Considerations: Be mindful of your diet. Avoiding overly acidic foods and beverages (like citrus fruits, sodas, and vinegar) can help reduce the sensation of acidity in your mouth.

4. Consult Your Doctor: If the sensation persists or worsens, it is essential to consult your healthcare provider. They can evaluate your medications and overall health to determine if any adjustments are necessary.

5. Saliva Substitutes: If dry mouth is a significant issue, consider using saliva substitutes or mouth rinses designed to alleviate dryness and maintain oral moisture.

In summary, the sensation of acidic saliva after taking medications can be attributed to reduced saliva production, which is a common side effect of many drugs. Maintaining hydration, practicing good oral hygiene, and consulting with your healthcare provider can help manage this condition effectively.

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