Impact of Flu Vaccine on Pediatric Five-in-One Immunization Schedule - Pediatrics

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The impact of the influenza vaccine on the schedule for administering the pentavalent vaccine?


Hello, Doctor! My baby was born on April 30, 1995, and is currently six months and 17 days old.
On November 6, the third dose of the pentavalent vaccine was originally scheduled to be administered at six months of age.
However, since my baby is eligible for the influenza vaccine this month, the doctor recommended administering the flu vaccine first.
Since this is the first dose, the second dose will need to be given next month (December).
As a result, the pentavalent vaccine will be postponed until January of next year, when my baby will be eight months old.
I am wondering if this will have any impact and whether it will affect the schedule for the next pentavalent vaccine dose.
Thank you very much for taking the time to respond to a new mother, Rosalin, amidst your busy work.

Rosalin, 30~39 year old female. Ask Date: 2006/11/17

Dr. Pei Rensheng reply Pediatrics


Hello: The flu vaccine and the pentavalent vaccine can be administered simultaneously, and the side effects will not be amplified.
If you are concerned that your child may feel more uncomfortable receiving two shots in one day, you can also choose to administer the flu vaccine and the pentavalent vaccine on different days.
Both of these vaccines are inactivated vaccines, so they can be given at any interval.
In your baby's case, it is also acceptable to administer the second dose of the flu vaccine one month later, followed by the pentavalent vaccine one month after that.
The schedule for the next administration of the fourth dose of the pentavalent vaccine will not be affected; it will still be given at 18 months of age! Wishing you health and happiness! Sincerely, Pei Ren-Sheng.

Reply Date: 2006/11/17

More Info


Hello Rosalin,
Thank you for your thoughtful question regarding the scheduling of the flu vaccine and the five-in-one immunization for your baby. It’s understandable to have concerns about the timing of vaccinations, especially for a new parent. Let’s break down the situation and clarify the implications of your current vaccination schedule.

Firstly, it’s important to note that both the flu vaccine and the five-in-one vaccine (which typically protects against diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b) are crucial for your child's health. The Centers for Disease Control and Prevention (CDC) recommends that children receive the flu vaccine annually, starting at six months of age. Since your baby is now six months and 17 days old, he is indeed eligible for the flu vaccine.

Regarding your original plan to administer the third dose of the five-in-one vaccine on November 6, it is perfectly acceptable to prioritize the flu vaccine, especially since it is the first time your baby will receive it. The flu vaccine is an inactivated vaccine, which means it does not contain live virus and is generally safe to administer alongside other vaccines. However, if your healthcare provider suggested spacing them out for comfort reasons, that is also a valid approach.

Now, concerning the delay of the five-in-one vaccine until January when your baby will be eight months old, this should not have any adverse effects on his health or immunity. Vaccination schedules are designed with flexibility in mind, and the most important factor is that your child receives all recommended doses within the appropriate time frames. The CDC guidelines indicate that the five-in-one vaccine can be administered as early as six months, and the timing can be adjusted as needed without compromising the effectiveness of the vaccine.

As for the subsequent doses of the five-in-one vaccine, the schedule typically continues with the fourth dose at 15-18 months of age, followed by a fifth dose at 4-6 years. Delaying the third dose by a couple of months will not affect the timing of the fourth dose; it will still be administered when your child reaches the appropriate age, which is 15-18 months.

In summary, your decision to administer the flu vaccine first is sound, and delaying the five-in-one vaccine until January will not negatively impact your child's health or vaccination schedule. It’s always best to follow the guidance of your healthcare provider, as they can tailor advice based on your child’s specific health needs and circumstances.

Lastly, it’s common for children to experience mild side effects after vaccinations, such as fever or irritability, but these are generally short-lived and a sign that the immune system is responding appropriately. If you have any further concerns or if your child experiences any unusual symptoms after vaccination, don’t hesitate to reach out to your healthcare provider.

Wishing you and your little one good health and happiness!
Best regards.

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