Adapalene: Key Questions About Acne Treatment and Care - Dermatology

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Question!


Active ingredient of Aikong gel: ADAPALENE
1.
Is this medication classified as a retinoid? Is it a third-generation retinoid?
2.
The instructions state to wash it off the next morning.
What happens if it is not washed off? Why is it necessary to wash it off?
3.
I've heard that topical retinoids are very effective for blackheads.
Is this also effective?
4.
What are the solutions for milia? Should they be extracted with a needle? Is cryotherapy an option? If cryotherapy is used, will the risk of post-inflammatory hyperpigmentation be significant?
5.
How should large comedones be treated?

Lai, 10~19 year old female. Ask Date: 2007/01/27

Dr. Huang Ruiyun reply Dermatology


1.
Yes.

2.
Don't you wash your face in the morning?
3.
The same.

4.
See a doctor for a needle aspiration.

5.
See a doctor for a needle aspiration.

Reply Date: 2007/01/27

More Info


Adapalene is a topical retinoid that is commonly used for the treatment of acne. It is indeed classified as a third-generation retinoid, which means it has been developed to provide effective acne treatment with fewer side effects compared to earlier generations of retinoids. Below, I will address your specific questions regarding Adapalene and provide additional insights into its use and acne treatment in general.

1. Is Adapalene a type of retinoid? Is it a third-generation retinoid?
Yes, Adapalene is a synthetic retinoid, which is a derivative of vitamin A. It is classified as a third-generation retinoid, designed to be more effective and less irritating than first and second-generation retinoids. This makes it a popular choice for treating acne, as it helps to regulate skin cell turnover, reduce inflammation, and prevent clogged pores.

2. Why does it say to wash it off the next morning? What happens if I don’t?
Typically, Adapalene is applied in the evening and left on overnight. The recommendation to wash it off in the morning may be specific to certain formulations or instructions given by a healthcare provider. Generally, it is not necessary to wash it off unless directed, as it is designed to be absorbed by the skin. If you do not wash it off, it may continue to exert its effects, but it could also lead to increased irritation or sensitivity, especially if you have sensitive skin. Always follow the specific instructions provided by your dermatologist or healthcare provider.

3. Is topical retinoid effective for blackheads?
Yes, topical retinoids like Adapalene are effective for treating blackheads. They work by promoting cell turnover and preventing the clogging of pores, which is a primary cause of blackheads. Regular use can help to reduce the formation of new blackheads and improve the overall texture of the skin.

4. What is the solution for milia? Should I use a needle or cryotherapy? Will cryotherapy cause significant pigmentation issues?
Milia are small, white cysts that can appear on the skin, often around the eyes and cheeks. They are typically harmless and can be treated through various methods. While some may opt for needle extraction, it is generally recommended to have this done by a dermatologist to avoid scarring or infection. Cryotherapy is another option, where liquid nitrogen is applied to freeze the milia. While cryotherapy can be effective, it may lead to temporary pigmentation changes, especially in individuals with darker skin tones. It is essential to discuss these options with a dermatologist to determine the best approach for your skin type.

5. How should large pimples be treated?
Large pimples, often referred to as cystic acne, can be more challenging to treat. It is advisable to avoid picking or squeezing them, as this can lead to scarring and infection. Topical treatments like Adapalene can help, but for more severe cases, a dermatologist may recommend oral medications such as antibiotics or hormonal treatments. Corticosteroid injections can also be used to reduce inflammation and size quickly. Again, consulting with a dermatologist is crucial for personalized treatment options.

In summary, Adapalene is a valuable tool in the management of acne, particularly for its ability to treat both inflammatory lesions and non-inflammatory lesions like blackheads. It is essential to follow the guidance of a healthcare professional when using this medication and to discuss any concerns regarding side effects or treatment efficacy. Regular follow-ups with a dermatologist can help tailor your acne treatment plan to achieve the best results while minimizing potential side effects.

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