Your Medications: Key Info on Clinoril, Prednisolone, Baclofen, and Erispan - Pharmacology

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Hello, I have experienced soreness due to overuse of the muscles in my temporomandibular joint (TMJ) and have seen a dentist who prescribed me several medications.
I would like to ask the pharmacist about the main actions of these medications, any precautions I should take while using them, and potential side effects.
The medications are Clinoril 200 mg tablet (Soliky), Prednisolone 5 mg tablet (Compesolon), Baclofen 5 mg tablet (Befon), and Erispan 0.25 mg tablet (ERA).
Thank you.

Ya Ya, 20~29 year old female. Ask Date: 2007/03/12

Dr. Chen Yuemei reply Pharmacology


Hello: Clinoril 200 mg is an anti-inflammatory pain reliever, Prednisolone 5 mg is a corticosteroid that serves as a potent anti-inflammatory medication, Baclofen 5 mg is a muscle relaxant, and Erispan 0.25 mg helps relax neuromuscular activity.
These medications are primarily used to reduce inflammation and relax overused muscles.
If the third and fourth medications are not taken before bedtime, they may cause drowsiness, so caution is advised when driving or operating hazardous machinery.
Short-term use of these medications typically does not warrant significant concern regarding side effects; you may discontinue them once your symptoms have improved.

Reply Date: 2007/03/12

More Info


Hello! Thank you for your inquiry regarding the medications Clinoril, Prednisolone, Baclofen, and Erispan. I understand that you are experiencing muscle soreness due to overuse in your temporomandibular joint (TMJ) area, and your dentist has prescribed these medications. Here’s a detailed overview of each medication, their primary actions, potential side effects, and important considerations for use.


1. Clinoril (Sulfinpyrazone) 200mg
Primary Action: Clinoril is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used to relieve pain and inflammation. It works by inhibiting the production of prostaglandins, which are chemicals in the body that promote inflammation, pain, and fever.

Indications: It is commonly prescribed for conditions such as arthritis, gout, and other inflammatory disorders.

Side Effects: Common side effects may include gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain. More serious side effects can include liver damage, kidney problems, and allergic reactions. It is important to monitor for any signs of gastrointestinal bleeding, such as black or bloody stools.

Considerations: Take Clinoril with food to minimize gastrointestinal discomfort. Avoid alcohol while taking this medication, as it can increase the risk of stomach bleeding. If you have a history of stomach ulcers or kidney disease, consult your doctor before use.


2. Prednisolone 5mg
Primary Action: Prednisolone is a corticosteroid that reduces inflammation and suppresses the immune response. It mimics the effects of hormones your body produces naturally in the adrenal glands.

Indications: It is used for a variety of conditions, including allergies, autoimmune diseases, and inflammatory conditions such as arthritis.

Side Effects: Potential side effects include weight gain, mood changes, increased appetite, and difficulty sleeping. Long-term use can lead to more serious effects like osteoporosis, high blood sugar, and increased risk of infections.

Considerations: It is important to follow your doctor’s instructions regarding dosage and duration of treatment. Do not suddenly stop taking Prednisolone without consulting your healthcare provider, as this can lead to withdrawal symptoms. Monitor for signs of infection, as corticosteroids can suppress the immune system.


3. Baclofen 5mg
Primary Action: Baclofen is a muscle relaxant that works by acting on the central nervous system to relieve muscle spasms.

Indications: It is commonly prescribed for muscle spasticity due to conditions such as multiple sclerosis or spinal cord injuries, but it can also be effective for muscle pain relief.

Side Effects: Common side effects include drowsiness, dizziness, weakness, and fatigue. Some individuals may experience confusion or hallucinations, particularly in older adults.

Considerations: Baclofen can cause sedation, so it is advisable to avoid driving or operating heavy machinery until you know how the medication affects you. Gradually increase the dosage as prescribed to minimize side effects. If you experience any severe side effects, such as difficulty breathing or severe dizziness, seek medical attention immediately.


4. Erispan (Eperisone) 0.25mg
Primary Action: Erispan is a muscle relaxant that helps relieve muscle tension and pain by acting on the central nervous system and peripheral nerves.

Indications: It is used for muscle spasms and pain associated with various musculoskeletal disorders.

Side Effects: Possible side effects include dizziness, drowsiness, and gastrointestinal disturbances. Rarely, it may cause allergic reactions or skin rashes.

Considerations: Similar to Baclofen, Erispan can cause sedation, so be cautious with activities that require alertness. It is important to take this medication as directed and report any unusual symptoms to your healthcare provider.


Conclusion
In summary, these medications can be effective in managing your symptoms related to muscle soreness and inflammation. However, it is crucial to be aware of their potential side effects and to follow your healthcare provider’s instructions closely. If you experience any concerning symptoms or have questions about your treatment plan, do not hesitate to reach out to your healthcare provider for further guidance. Always ensure that you are taking these medications as prescribed and report any adverse effects promptly. Wishing you a speedy recovery!

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