Managing Unexpected Pregnancy While on Medication: Risks and Options - Gastroenterology and Hepatology

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Can D&C treat unintended pregnancy?


Dr.
Hsu: Hello, my pre-treatment GOT/GPT levels were 120/64.
After taking Danazol for four months, my liver enzymes have returned to normal at 19/17, but the E antigen remains positive.
I have been on medication for over a year now, and it still has not converted to negative (liver function remains normal).
Recently, I discovered an unexpected pregnancy.
Should I definitely terminate the pregnancy? Is there a risk of teratogenic effects? Are there any other management options? Thank you for your response!

Liu Xiaojie, 20~29 year old female. Ask Date: 2007/04/13

Dr. Xu Jinchuan reply Gastroenterology and Hepatology


Hello Ms.
Liu! After inquiring with the pharmaceutical company, there is limited safety data regarding the use of Ganoderma lucidum (Reishi mushroom) during human pregnancy.
In reproductive studies conducted on animals, there is no evidence indicating that Ganoderma lucidum has teratogenic effects or affects the fertility of males or females.
Therefore, the current information regarding the impact of Ganoderma lucidum on pregnancy is limited to animal studies, and there is no data available on its effects during human pregnancy.
Our recommendation is that individuals who have used or plan to use Ganoderma lucidum for treatment should ideally avoid pregnancy for at least two years.

Reply Date: 2007/04/13

More Info


Managing an unexpected pregnancy while on medication can be a complex and emotionally charged situation. It is essential to approach this matter with careful consideration of both the health of the mother and the developing fetus. In your case, you have been on medication for hepatitis B, specifically干安能 (which is likely a form of antiviral treatment), and have recently discovered that you are pregnant.
Firstly, it is crucial to understand the implications of your current medication on the pregnancy. Many medications can have varying effects during pregnancy, particularly in the first trimester when the fetus is most vulnerable to teratogenic effects (the potential to cause birth defects). The concern about potential teratogenic effects is valid, especially with antiviral medications, as some can cross the placenta and affect fetal development. However, not all antiviral medications carry the same risks, and some may be considered safer than others during pregnancy.

In your case, the fact that your liver function tests (GOT/GPT) have normalized is a positive sign, but the persistence of the E antigen indicates that the virus is still present in your system. This raises the question of whether continuing your medication is necessary for your health and whether it poses a risk to the pregnancy.
It is essential to consult with both your obstetrician and your hepatologist (liver specialist) to discuss the risks and benefits of continuing your medication during pregnancy. They can provide you with tailored advice based on your specific health situation, the type of medication you are taking, and the stage of your pregnancy.
In many cases, if the medication is deemed necessary for the mother's health, it may be possible to continue treatment with close monitoring. Some antiviral medications have been used safely in pregnant women, and the benefits of controlling the viral load may outweigh the potential risks to the fetus.
If there are significant concerns about the medication's effects on the fetus, your healthcare providers may discuss alternative treatment options or adjustments to your current regimen. It is also important to consider the potential consequences of discontinuing treatment, such as the risk of liver disease progression or complications from hepatitis B.

Ultimately, the decision to continue or discontinue the pregnancy should be made based on a thorough understanding of the risks involved, both to the mother and the fetus. If there are significant risks of severe birth defects or other complications, your healthcare team will help you weigh these factors carefully.
In summary, it is not a foregone conclusion that you must terminate the pregnancy due to the medication you are taking. Open communication with your healthcare providers is key to making an informed decision that prioritizes both your health and the health of your baby. They will guide you through the options available, ensuring that you have the support and information needed to navigate this challenging situation.

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