Chronic Back Pain: Seeking Solutions After 3.4 Years of Suffering - Orthopedics

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Lower back pain for 3.4 years?


Hello Doctor: I have been experiencing lower back pain since high school, and it has persisted for about 3 to 4 years now.
Recently, the pain has worsened over the past six months, and it even hurts when I walk.
The pain radiates from my lower back down to my thighs and extends to my knees.
I have been seeing a rheumatologist every month during this time, and the doctor diagnosed me with seronegative spondyloarthritis.
Despite visiting the same hospital for 3 to 4 years, my pain has not improved; in fact, it has gotten worse.
Currently, I am taking the following medications: Naposin (one tablet after breakfast and dinner), Plaquenil (one tablet after breakfast and dinner), Colchicine (1/4 tablet after breakfast and dinner), Prednisolone (half a tablet after breakfast and dinner), and Stacaine (one tablet after breakfast and dinner).
I also have G6PD deficiency.
I have been on these medications for several years without significant improvement, and I would like to seek a second opinion from a different physician.

Xiao Hong, 20~29 year old female. Ask Date: 2007/05/22

Dr. Lin Xiaoyi reply Orthopedics


Hello, Xiao Hong: If a diagnosis of seronegative spondyloarthritis is confirmed, the most commonly used immunomodulator is Salazopyrin (sulfasalazine).
However, patients with G6PD deficiency may not be suitable for this type of medication (depending on the severity of the enzyme deficiency), which may be why your physician prescribed other medications for you.
The medications you are taking include: Naposin, which is a non-steroidal anti-inflammatory drug (NSAID); Plaquenil, which is an immunomodulator commonly used for rheumatoid arthritis, systemic lupus erythematosus, and other autoimmune diseases; colchicine, which is often used for gout, vasculitis, and oral ulcers; prednisolone, which is a steroid; and Stacaine, which is a gastric medication.
In theory, taking NSAIDs and steroids should improve the symptoms of most seronegative spondyloarthritis.
If there is no improvement at all, it may be worth considering the possibility of other conditions, such as symptoms from nerve compression.
Since I have not seen you in person and have no physical examination, laboratory tests, or X-ray references, the above analysis should only be taken as a reference.
I recommend that you find a trusted physician to follow up on your condition and discuss treatment options.
Wishing you good health.
Lin Hsiao-Yi, Department of Allergy, Immunology, and Rheumatology, Taipei Veterans General Hospital.

Reply Date: 2007/05/22

More Info


Chronic back pain can be a debilitating condition that significantly impacts daily life, and it is understandable that after 3.4 years of suffering, you are seeking alternative solutions. Your diagnosis of seronegative spondyloarthritis indicates an inflammatory condition that can affect the spine and other joints, leading to pain and stiffness. The medications you are currently taking, including Naposin (a non-steroidal anti-inflammatory drug), Plaquenil (an antimalarial that can also help with autoimmune conditions), Colchicine (often used for gout), Prednisolone (a corticosteroid), and Stacaine (a local anesthetic), suggest that you are under a comprehensive treatment plan. However, it appears that this regimen has not provided the relief you need.

Given your ongoing pain, it may be beneficial to explore additional treatment options. Here are some strategies that could be considered:
1. Physical Therapy: Engaging in a structured physical therapy program can be highly beneficial for chronic back pain. A physical therapist can design a personalized exercise regimen that focuses on strengthening the core muscles, improving flexibility, and enhancing overall mobility. Techniques such as manual therapy, stretching, and specific exercises can help alleviate pain and improve function.

2. Pain Management Clinics: Consider consulting a pain management specialist who can offer a multidisciplinary approach to your pain. This may include interventional procedures such as epidural steroid injections, nerve blocks, or even newer techniques like radiofrequency ablation, which can help manage pain more effectively.

3. Alternative Therapies: Acupuncture, chiropractic care, and massage therapy have been reported to provide relief for some individuals with chronic pain. While these therapies may not work for everyone, they can be worth exploring as adjuncts to your current treatment plan.

4. Lifestyle Modifications: Incorporating regular low-impact aerobic exercises, such as swimming or cycling, can help maintain mobility without putting excessive strain on your back. Additionally, maintaining a healthy weight can reduce stress on your spine and joints.

5. Diet and Nutrition: Since you have a history of favism (a condition triggered by certain foods), it is essential to ensure that your diet is well-balanced and avoids any triggers. Some studies suggest that anti-inflammatory diets rich in omega-3 fatty acids, antioxidants, and whole foods may help reduce inflammation and pain.

6. Psychological Support: Chronic pain can take a toll on mental health. Cognitive-behavioral therapy (CBT) or other forms of psychological support can help you develop coping strategies to manage pain and improve your quality of life.

7. Reevaluation of Medications: Since you have been on your current medication regimen for several years without significant improvement, it may be worthwhile to discuss with your rheumatologist or another specialist the possibility of adjusting your medications. There are various biologic therapies available for spondyloarthritis that may provide better control of inflammation and pain.

8. Regular Follow-ups: Continue to have regular follow-ups with your healthcare providers to monitor your condition and make necessary adjustments to your treatment plan. It may also be helpful to seek a second opinion from another rheumatologist or pain specialist who may offer different insights or treatment options.

In conclusion, chronic back pain, especially related to inflammatory conditions like seronegative spondyloarthritis, can be complex and challenging to manage. A multidisciplinary approach that includes physical therapy, pain management strategies, lifestyle modifications, and possibly a reevaluation of your current medications may provide you with the relief you are seeking. It is essential to advocate for your health and explore all available options to improve your quality of life.

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