Do Eye Drops Like Fluorometholone Transfer to Breast Milk? - Pharmacology

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Do antibiotic or steroid eye drops prescribed by an ophthalmologist, such as Fluorometholone, transfer into breast milk and get absorbed into the body of a child, similar to oral medications?

meimei, 20~29 year old female. Ask Date: 2007/06/21

Dr. Shou Weijin reply Pharmacology


Ophthalmic solutions do not require much concern regarding their effects on pregnant or lactating women, as the bioavailability of these solutions is only 1-3%.
This means that when one drop of eye medication is administered, at most only 3% is absorbed by the body.
Furthermore, after metabolism and excretion, the amount that could potentially transfer into breast milk is negligible.
Therefore, the systemic impact of topical eye drops on the body is very minimal.

Reply Date: 2007/06/21

More Info


When it comes to the transfer of medications, including eye drops like Fluorometholone, into breast milk, it's essential to understand the pharmacokinetics of the drug and the potential implications for breastfeeding mothers and their infants.

Fluorometholone is a corticosteroid used primarily to treat inflammation in the eyes. It is a relatively low-potency steroid that is often prescribed for conditions such as allergic conjunctivitis or post-operative inflammation. The concern regarding the transfer of medications into breast milk is valid, as many drugs can pass into breast milk to varying degrees.

Research indicates that most topical medications, including eye drops, have a low systemic absorption rate. This means that when applied to the eyes, only a small amount of the drug enters the bloodstream. Consequently, the amount that could potentially transfer into breast milk is usually minimal. However, the exact concentration of Fluorometholone in breast milk has not been extensively studied, and while it is likely to be low, it is not entirely absent.

The general consensus among healthcare professionals is that the use of Fluorometholone and similar eye drops is considered relatively safe during breastfeeding. The American Academy of Pediatrics categorizes Fluorometholone as a medication that is usually compatible with breastfeeding, meaning that the benefits of treating the mother's condition may outweigh any potential risks to the infant.

However, it is crucial for breastfeeding mothers to consult with their healthcare provider before using any medication, including eye drops. The healthcare provider can assess the specific situation, including the mother's health condition, the necessity of the medication, and any potential risks to the infant. If a mother is concerned about the effects of Fluorometholone or any other medication on her breastfed child, she should discuss alternative treatments or the timing of medication administration to minimize any potential exposure.

In summary, while Fluorometholone may transfer into breast milk, the amount is likely to be minimal, and it is generally considered safe for use during breastfeeding. Nonetheless, individual circumstances can vary, and it is always best to seek personalized medical advice from a healthcare professional. This ensures that both the mother's health and the infant's safety are prioritized.

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