Safety and Side Effects of Antiepileptic Drugs After Brain Surgery

Antiepileptic drugs

Hello Dr.
Huang,
I underwent surgery for a cerebral aneurysm at the end of July and have been taking the antiepileptic medication Aleviatin 100 mg three times a day since then.
Is this dosage safe? Compared to another medication, Trileptal 300 mg twice a day, which one has fewer side effects?
P.S.
I am a hepatitis B carrier and have been monitoring my GOP, GTP, and ALP levels for 20 years, all of which have been normal.

Best regards,
Mr.
Zhang

Mr. Zhang, 50~59 year old female. Ask Date: 2007/09/13

Dr. Huang Yingzhe reply Neurology

Dear Mr.
Chang,
Dr.
Huang Ying-Che, Director of the Neurology Department at Tainan Hospital, Ministry of Health and Welfare, would like to inform you that Aleviatin is a very safe and commonly used medication, and there are no issues with its use.
It is recommended that there is no need to change your medication.
As for side effects, they can vary from person to person (although new medications may claim to have fewer side effects, they can still occur at times).
The Tainan Hospital wishes you good health and all the best!
Best regards.

Reply Date: 2007/09/13

More Info

When considering the safety and side effects of antiepileptic drugs (AEDs) after brain surgery, it is essential to understand the individual characteristics of the medications involved, as well as the patient's overall health status. In your case, you are currently taking Aleviatin (also known as Lacosamide) and are comparing it to Trileptal (Oxcarbazepine).
Aleviatin is generally regarded as a safe and effective AED, particularly for patients who have undergone brain surgery. It works by stabilizing electrical activity in the brain, which can help prevent seizures. The common side effects of Aleviatin include dizziness, headache, nausea, and fatigue. However, it is important to note that side effects can vary significantly from person to person. Some patients may tolerate Aleviatin very well, while others may experience more pronounced side effects.

On the other hand, Trileptal is another commonly used AED that is effective in controlling seizures. It is known for having a relatively favorable side effect profile as well. Common side effects of Trileptal include dizziness, drowsiness, double vision, and nausea. One of the advantages of Trileptal is that it has a lower risk of causing severe allergic reactions compared to some other AEDs.

When comparing the two medications, it is crucial to consider your specific health conditions, particularly your status as a chronic Hepatitis B carrier. Both Aleviatin and Trileptal are generally considered safe for patients with Hepatitis B, but it is always best to consult with your healthcare provider regarding any potential interactions or side effects that may be exacerbated by your liver condition.

In terms of side effects, while both medications can cause dizziness and fatigue, the severity and frequency of these side effects can differ among individuals. Some studies suggest that Aleviatin may have a slightly lower incidence of certain side effects compared to Trileptal, but this can vary based on individual responses.

Given your history of brain surgery and the need for effective seizure control, it is essential to maintain open communication with your healthcare provider. If you are experiencing any concerning side effects or if you feel that your current medication is not adequately controlling your seizures, it is important to discuss this with your doctor. They may consider adjusting your dosage or switching to a different AED that may be better tolerated.

In conclusion, both Aleviatin and Trileptal are considered safe options for managing seizures after brain surgery, but individual responses can vary. It is crucial to work closely with your healthcare provider to monitor your condition and make any necessary adjustments to your treatment plan. Regular follow-ups and open discussions about your medication's effectiveness and side effects will help ensure that you receive the best possible care tailored to your specific needs.

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