Differences Between Ponstan and Mefenamic Acid: What You Need to Know

Ponstan and Mefenamic Acid refer to the same medication. Ponstan is a brand name for Mefenamic Acid, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, including

Hello, I previously visited a dentist who prescribed Ponstan 500mg for anti-inflammatory and analgesic purposes.
I was advised to stop using it if I experienced any allergic symptoms, as I am allergic to Aspirin.
After taking it, I did not have any allergic reactions.
Later, for other reasons, I went to the pharmacy and showed the pharmacist the name Ponstan, and he gave me a box of "Sutan," which contains Mefenamic Acid 500mg.
After confirming several times, he said that these two are the same.
I found information online that also stated they are the same medication, so I felt reassured and took one capsule.
However, shortly after, I developed allergic symptoms (swelling and redness of the eyelids, fever, and cold-like symptoms).
Are these two ingredients truly the same, or could there be another reason for my reaction? Thank you!

no, 20~29 year old female. Ask Date: 2007/11/04

Dr. Liao Huiling reply Pharmacology

Hello! The active ingredient in Ponstan is indeed Mefenamic Acid.
This medication belongs to the class of "non-steroidal anti-inflammatory drugs" (NSAIDs), and there is a high likelihood of experiencing allergic reactions.
Please inform your doctor about your allergy to "Mefenamic Acid" during your next visit, so that alternative pain relief medications can be prescribed to avoid a recurrence of the allergy.
Wishing you health and happiness!

Reply Date: 2007/11/04

More Info

Ponstan and Mefenamic Acid are indeed the same medication. Ponstan is a brand name for Mefenamic Acid, which is a non-steroidal anti-inflammatory drug (NSAID) commonly used for pain relief, inflammation reduction, and fever control. It is important to note that while the active ingredient is the same, individual responses to medications can vary significantly due to several factors, including allergies, sensitivities, and individual health conditions.

In your case, you mentioned that you have a known allergy to Aspirin (acetylsalicylic acid), which is also an NSAID. While Mefenamic Acid is chemically distinct from Aspirin, it is still possible for individuals with a history of NSAID allergies to experience allergic reactions to other NSAIDs, including Mefenamic Acid. This could explain the allergic symptoms you experienced after taking the medication, such as eyelid swelling, fever, and flu-like symptoms.
Allergic reactions can manifest in various ways, including skin rashes, swelling, respiratory issues, and gastrointestinal distress. In some cases, individuals may not react to one NSAID but may have an adverse reaction to another, even if they are not chemically identical. This phenomenon is known as cross-reactivity, and it is particularly relevant for individuals with a history of drug allergies.

Given your experience, it is crucial to inform your healthcare provider about your reaction to Mefenamic Acid. They may recommend avoiding this medication in the future and suggest alternative pain relief options that do not belong to the NSAID class, such as acetaminophen (Tylenol) or other medications that are less likely to trigger an allergic response.

In summary, while Ponstan and Mefenamic Acid are the same in terms of their active ingredient, individual reactions can differ based on personal health history and sensitivities. It is always advisable to consult with a healthcare professional before starting any new medication, especially if you have a history of allergies or adverse reactions to similar drugs. Your safety and well-being should always be the top priority when managing pain or inflammation.

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