Confusion
Hello! I have a perplexing question.
A patient fell from a height and sustained an L3 burst fracture.
After being admitted to the hospital, they underwent surgery for internal fixation.
On the third day post-surgery, the patient began to experience fever.
Despite multiple sets of bacterial cultures from the spine showing normal results, the infectious disease physician suspects the fever may be related to the surgical wound, which is red and swollen.
The patient underwent debridement in the operating room.
Sputum cultures for Haemophilus influenzae were also conducted.
The patient has been on vancomycin and cefmetazole antibiotic treatment for a month.
HIV screening was negative, VDRL was positive, but TPHA was negative.
The patient's WBC, segmented neutrophils, CRP, and ESR levels remain elevated, while hemoglobin levels are consistently between 9-10 mg/dL.
Anti-infective treatment has been ongoing for a long time, yet the patient continues to have fever.
There is no history of rheumatoid arthritis or systemic lupus erythematosus.
The patient still reports back pain, leg pain, numbness, and weakness.
It has been a month since the surgery, and while urination was normal previously, the patient has recently experienced difficulty urinating, requiring prolonged massage to void.
The cause of these issues remains unknown.
Lun, 20~29 year old female. Ask Date: 2008/01/16
Dr. Zhang Yuanyi reply Neurosurgery
Dear Mr.
Lun,
Hello, when considering infection issues, there are many factors to take into account.
The most common sites are still the lungs, urinary tract, and surgical sites.
It is also important to consider the pattern of fever; if it has led to myelitis, then general antibiotic treatment typically needs to last for 6-8 weeks or more.
If no sterile cultures are obtained, it may complicate the physician's choice of medication.
Regarding the symptoms of foot pain, numbness, and weakness, it is essential to assess the location and severity.
If a lumbar vertebral fracture has caused nerve damage from the outset, the injured nerves generally require several days of observation to see if they can recover.
Additionally, if there is an infection of the spinal cord (vertebrae), it may also affect nerve function.
The patient must consider many directions in this case, and it is advisable to discuss thoroughly with the attending physician.
Wishing you peace and health.
Sincerely,
Dr.
Zhang Yuan-yi
Attending Neurosurgeon
Taoyuan Hospital, Department of Health
Reply Date: 2008/01/16
More Info
Post-surgery complications, particularly fever and urinary difficulties, can be quite concerning, especially in patients who have undergone significant procedures like spinal surgery. In the case you presented, the patient experienced a burst fracture of the L3 vertebra, underwent surgical fixation, and subsequently developed a fever three days post-operation. This situation raises several important considerations regarding potential causes and management strategies.
Firstly, fever following surgery can arise from various sources. Infections are a primary concern, particularly surgical site infections (SSIs), urinary tract infections (UTIs), and pneumonia. The fact that multiple bacterial cultures from the spine have returned negative is reassuring but does not entirely rule out an infection. It is essential to consider that some infections may not be easily detectable through standard cultures, especially if they are caused by atypical organisms or if the patient is on antibiotics that could suppress bacterial growth.
The persistent elevation of inflammatory markers such as white blood cell count (WBC), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) suggests an ongoing inflammatory process. This could be due to a localized infection at the surgical site, which may not have been adequately addressed, or it could reflect a systemic response to the trauma and surgery itself. The presence of redness and swelling at the surgical site further supports the possibility of an infection, and the decision to perform debridement indicates that the surgical team is taking these signs seriously.
The patient's urinary difficulties, which developed after surgery, are also noteworthy. Initially, the patient had normal urination, but the recent onset of difficulty could indicate a few potential issues. One possibility is that the surgical procedure may have inadvertently affected the nerves that control bladder function, particularly if there was any manipulation or trauma to the lumbar region during surgery. Another consideration is the development of a urinary tract infection, which can occur post-operatively and may present with symptoms such as urgency, frequency, and difficulty initiating urination.
Given the complexity of this case, it is crucial for the healthcare team to conduct a thorough evaluation. This should include imaging studies to assess for any complications such as abscess formation or hematoma that could be contributing to the symptoms. Additionally, a urology consultation may be warranted to evaluate the urinary difficulties further, especially if there is a suspicion of neurogenic bladder or other urological complications.
In terms of management, the patient is already on broad-spectrum antibiotics (vancomycin and cefmetazole), which is appropriate given the concern for infection. However, if the fever persists despite adequate antibiotic therapy, it may be necessary to reassess the situation. This could involve switching to different antibiotics based on culture results or considering the need for additional surgical intervention if an abscess or other complication is identified.
In conclusion, post-surgical fever and urinary difficulties in a patient who has undergone spinal surgery require careful evaluation and management. The healthcare team should continue to monitor the patient closely, consider further diagnostic workup, and adjust treatment as necessary based on clinical findings and laboratory results. Open communication with the patient and their family about the potential complications and the rationale for ongoing investigations is also essential to ensure understanding and cooperation in the management plan.
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