Post-Injection Numbness and Pain: Is Nerve Damage Possible? - Neurology

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Numbness, weakness, and pain after receiving an injection in the arm?


Hello Doctor,
I would like to ask about my mother.
She has been experiencing significant pain in her right hand due to overuse (from household chores and work).
She visited an orthopedic doctor and received an injection for what was diagnosed as tendonitis, but her condition worsened afterward.
My mother is concerned that the injection may have affected a nerve, leading to increased numbness and pain.
Is there a possibility of this happening? If so, are there any methods for improvement? Thank you for your response.

eva, 20~29 year old female. Ask Date: 2008/03/29

Dr. Gao Chunde reply Neurology


First, it is important to identify the injection site.
Generally, unless there are specific needs, physicians will avoid injecting into nerves and will try to steer clear of areas where nerves may be present to prevent complications.
Secondly, regarding the condition, in addition to tendonitis, there may be an emerging nerve issue, such as cervical nerve root involvement, brachial plexus issues, or even a localized peripheral nerve lesion.
If the situation continues to progress, it is advisable to seek care from a neurologist promptly.

Reply Date: 2008/03/29

More Info


Post-injection numbness and increased pain can indeed raise concerns about potential nerve damage, especially in the context of a corticosteroid or anesthetic injection aimed at treating conditions like tendonitis or other musculoskeletal issues. While it is not uncommon for patients to experience temporary discomfort or exacerbation of symptoms following an injection, it is essential to differentiate between normal post-procedural reactions and signs of potential nerve injury.

When a patient receives an injection in the vicinity of nerves, there is a risk, albeit small, of inadvertently affecting those nerves. This can occur due to direct trauma from the needle, chemical irritation from the injected substance, or even due to swelling and inflammation that can occur post-injection. Symptoms of nerve injury can include numbness, tingling, burning sensations, or increased pain in the area supplied by the affected nerve. In your mother's case, the worsening of her symptoms following the injection could suggest that the injection may have impacted the nearby nerves, particularly if she is experiencing new or intensified numbness and pain.

It is important to note that while nerve damage is a possibility, it is not the only explanation for her increased symptoms. In some cases, the underlying condition may continue to progress despite treatment, or the injection itself may provoke a temporary inflammatory response that can lead to increased pain. According to studies, approximately 20% of patients may experience a temporary worsening of pain after injections, often resolving within a few days to weeks.

If nerve damage is suspected, it is crucial to seek further evaluation from a healthcare professional. A thorough clinical assessment, including a detailed history and physical examination, can help determine the cause of her symptoms. Additional diagnostic tests, such as electromyography (EMG) or nerve conduction studies (NCS), may be warranted to assess nerve function and identify any potential damage.

In terms of management, if nerve damage is confirmed, treatment options may include:
1. Physical Therapy: Engaging in a tailored physical therapy program can help improve strength, flexibility, and function while addressing pain.

2. Medications: Non-steroidal anti-inflammatory drugs (NSAIDs) or neuropathic pain medications (like gabapentin or pregabalin) may be prescribed to help manage pain and discomfort.

3. Corticosteroid Injections: If inflammation is a significant factor, additional corticosteroid injections may be considered, but this should be approached cautiously, especially if there is a concern about nerve involvement.

4. Surgical Intervention: In cases of significant nerve compression or damage, surgical options may be explored to relieve pressure on the affected nerve.

5. Alternative Therapies: Techniques such as acupuncture, massage therapy, or chiropractic care may provide symptomatic relief for some patients.

It is essential for your mother to communicate her symptoms clearly to her healthcare provider, who can then tailor a management plan based on her specific situation. If her symptoms persist or worsen, a referral to a specialist, such as a neurologist or pain management specialist, may be beneficial for further evaluation and treatment options.

In conclusion, while post-injection numbness and pain can raise concerns about nerve damage, it is crucial to conduct a thorough evaluation to determine the underlying cause. With appropriate management and follow-up, many patients can find relief from their symptoms and improve their quality of life.

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