Nerve Sensations After Injections: Causes and Concerns - Neurology

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Numbness in the leg after an injection?


Hello, doctor.
A neurosurgeon administered glucose prolotherapy to me, injecting it into the back of my knee.
During the injection, it stimulated a nerve, causing my calf to go numb all the way to the sole of my foot.
I reported this to the doctor, who then changed the injection site, and the numbness did not occur again.
After returning home, I felt fine for several days, but just now, while bending my knee to trim my toenails for about 30 seconds, I felt a tingling sensation in the sole of my foot when I straightened my leg.
I have never experienced this sensation before.
I have spinal stenosis at the third and fourth lumbar vertebrae, and while I usually have lower back pain, my legs do not typically feel numb.
Doctor, could it be that the injection caused some nerve damage at that time? In cases like this, where an injection stimulates a nerve, can it cause harm to the nerve? Thank you.

Mimi, 40~49 year old female. Ask Date: 2021/12/10

Dr. Jiang Junyi reply Neurology


Hello Ms.
Mi: You mentioned that "it only takes about 30 seconds to trim my toenails while bending my knees, and when I stretch my legs, I feel a tingling sensation in the soles of my feet." Your symptoms seem to be posture-related, and it may be worth considering peripheral nerve compression, although the affected area is not at the L3-L4 level.
It may be necessary to consider the nerve roots at L5 or S1.
I recommend that you visit a neurology or rehabilitation clinic for evaluation (such as nerve conduction studies and electromyography) and treatment.
The physician will prescribe medication and rehabilitation therapy based on your condition.
Thank you for your inquiry, and feel free to discuss any related questions! Wishing you good health and peace.
Dr.
Jiang Junyi from Taoyuan Hospital cares about you.

Reply Date: 2021/12/10

More Info


When it comes to nerve sensations following injections, particularly in the context of your experience with glucose prolotherapy in the knee, it’s essential to understand the underlying mechanisms and potential implications.
Firstly, it’s not uncommon for patients to experience transient sensations such as numbness or tingling in the extremities after an injection, especially if the needle inadvertently comes into contact with a nerve. This can happen due to the anatomical proximity of nerves to the injection site. In your case, the sensation of your calf and foot becoming momentarily numb during the injection could indicate that the needle was close to or briefly irritated a nerve. Fortunately, this sensation often resolves quickly, as you experienced when the injection was repositioned.

However, the persistence of numbness or tingling after the injection, especially when bending or straightening your knee, raises some concerns. Given your history of spinal stenosis at the third and fourth lumbar vertebrae, it’s possible that the existing nerve compression could be exacerbated by the injection or the position of your leg during activities like cutting your toenails. The lumbar spine can influence the sensation in the legs, and any additional pressure or irritation can lead to symptoms like the ones you described.

In terms of whether the injection could have caused lasting nerve damage, it’s important to note that while nerve injuries can occur, they are relatively rare, especially with experienced practitioners. Most cases of nerve irritation from injections are temporary and resolve with time. However, if the nerve is significantly compressed or damaged, symptoms could persist longer.
To address your concerns, here are a few points to consider:
1. Transient vs. Permanent Symptoms: Many patients experience temporary nerve sensations after injections, which typically resolve within days to weeks. If your symptoms persist or worsen, it would be prudent to follow up with your healthcare provider for further evaluation.

2. Monitoring Symptoms: Keep track of any changes in your symptoms. If you notice increased numbness, weakness, or pain, especially if it spreads or becomes more severe, seek medical attention promptly.

3. Physical Therapy: Engaging in physical therapy may help alleviate some of the discomfort associated with your spinal stenosis and improve overall nerve function. A physical therapist can provide exercises tailored to your condition.

4. Follow-Up with Your Doctor: It’s crucial to maintain open communication with your healthcare provider. Discuss your symptoms in detail, including their onset, duration, and any activities that exacerbate them. This information can help your doctor determine the best course of action.

5. Potential for Nerve Recovery: Nerves have a remarkable ability to heal, and many patients recover fully from transient nerve irritation. However, the timeline for recovery can vary based on individual circumstances.

In conclusion, while your experience of numbness following the injection is concerning, it is not uncommon and may resolve with time. However, given your history of spinal stenosis and the nature of your symptoms, it is advisable to consult with your healthcare provider for a thorough assessment and to rule out any significant nerve injury. They may recommend imaging studies or further evaluations to ensure that your symptoms are appropriately addressed.

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