Elevated Liver Enzymes: What You Need to Know - Gastroenterology and Hepatology

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Abnormal liver function tests?


Hello Dr.
Lin: I just received the results of my military service physical examination from the city office today.
It states that my liver enzyme levels are elevated, with SGOT at 58 and SGPT at 84.
I checked online, and the normal range is considered to be within 40, but some doctors say that levels under 100 are still normal.
If levels under 100 are considered normal, why did the military service department indicate that my liver enzyme levels are abnormal? I'm unclear about which information is correct.
Recently, I have been staying up late frequently due to preparing for graduate school exams.
My SGPT is more than double the normal value, and I am really worried about the severity of my liver condition.
What can I do to lower my liver enzyme levels? Does the liver have the ability to repair itself? What should I do to maintain liver health? I am truly concerned, and I would appreciate your guidance.

Amin, 20~29 year old female. Ask Date: 2008/05/15

Dr. Lin Minghui reply Gastroenterology and Hepatology


Hello A-Min,
Although the standard values for GOT and GPT may vary slightly from one hospital to another, they generally do not differ significantly.
In our hospital, the standard values for GOT and GPT are below 40.
A GPT level of 84 indicates an abnormal liver index, suggesting liver inflammation and an abnormal index phenomenon.
Generally, when liver indices are abnormal, it is important to identify the underlying cause, such as the presence of viral hepatitis.
In Taiwan, it is crucial to be aware of chronic hepatitis B and C.
Additionally, fatty liver, medications, alcohol, and chemical substances can also lead to hepatitis, as well as autoimmune diseases and metabolic disorders.
1.
It is essential to identify the cause of liver abnormalities to provide targeted treatment: abstain from alcohol for alcohol-related issues, control weight for obesity, and consider antiviral medication for viral hepatitis.
2.
An abdominal ultrasound can be performed to check for any liver lesions.
3.
To maintain liver health, it is advisable to keep a positive mood, avoid staying up late, manage work and study stress, engage in moderate exercise, maintain a balanced diet, and avoid spicy foods and those with excessive artificial additives.
Wishing you good health,
Dr.
Lin Ming-Hui, Taoyuan Hospital, Department of Health

Reply Date: 2008/05/15

More Info


Elevated liver enzymes, specifically SGOT (AST) and SGPT (ALT), are common indicators of liver health and function. In your case, SGOT is at 58 and SGPT at 84, both of which exceed the typical upper limit of 40. While some sources may suggest that values under 100 are acceptable, it’s essential to understand that any elevation can indicate liver stress or damage, and the interpretation of these values can vary based on individual circumstances and the context of the overall health picture.

Liver enzymes are proteins that help facilitate various biochemical reactions in the liver. When liver cells are damaged or inflamed, these enzymes leak into the bloodstream, leading to elevated levels. Common causes of elevated liver enzymes include viral hepatitis, alcohol consumption, fatty liver disease, medication effects, and metabolic disorders. Given your recent stress from studying for exams and potential lifestyle factors like late nights, it’s possible that these could have contributed to your elevated levels.

To address your concerns about the severity of your liver condition, it’s important to consider several factors. First, while your enzyme levels are elevated, they do not necessarily indicate severe liver damage. The liver has a remarkable ability to heal itself, especially if the underlying cause of the damage is addressed. For instance, if your elevated enzymes are due to lifestyle factors such as poor diet, lack of exercise, or excessive alcohol consumption, making positive changes can significantly improve your liver health.

Here are some steps you can take to help lower your liver enzyme levels and promote overall liver health:
1. Healthy Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid processed foods, high-fat foods, and sugars. Foods high in antioxidants, such as berries and leafy greens, can be particularly beneficial.

2. Hydration: Drink plenty of water to help your liver function optimally and flush out toxins.

3. Limit Alcohol: If you consume alcohol, consider reducing your intake or abstaining altogether, as alcohol can exacerbate liver damage.

4. Regular Exercise: Engage in regular physical activity to maintain a healthy weight and improve liver function. Aim for at least 150 minutes of moderate aerobic activity each week.

5. Avoid Toxins: Minimize exposure to environmental toxins and chemicals, including certain medications that can stress the liver.

6. Regular Check-ups: Follow up with your healthcare provider for regular monitoring of your liver enzymes and overall health. They may recommend further testing, such as imaging studies or additional blood tests, to assess liver function and rule out any underlying conditions.

7. Stress Management: Since stress can impact your overall health, consider incorporating stress-reducing activities into your routine, such as yoga, meditation, or deep-breathing exercises.

8. Sleep Hygiene: Ensure you are getting adequate sleep, as rest is crucial for recovery and overall health.

In conclusion, while your elevated liver enzymes are a cause for attention, they do not necessarily indicate a severe problem. The liver is capable of self-repair, especially with lifestyle modifications. It’s essential to consult with your healthcare provider for personalized advice and to determine if further evaluation is necessary. Regular monitoring and proactive health management can help you maintain a healthy liver and overall well-being.

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