Why Did My Skin Break Out After Using Allergy Cream? - Dermatology

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Why do I develop a lot of acne after applying allergy medication?


I would like to ask, last week I improperly used alpha hydroxy acid, which caused some redness on my cheekbones.
I immediately went to see a doctor and received an allergy cream, which helped reduce the redness after two days.
However, on the third day, my cheeks became filled with small bumps, which scared me.
I checked the ingredients of the allergy cream and found that it contained an antifungal medication called Comybor cream.
I was puzzled and wondered if it was the culprit behind my facial bumps.
When I returned for a follow-up, the doctor surprisingly said it was acne.
My face was becoming increasingly bumpy, with inflamed comedones.
The doctor prescribed me a topical medication called Panoxyl, but after applying it, my face became red, swollen, and blotchy again in the morning.
Eventually, the doctor gave me an injection, which helped reduce the redness, but my skin still feels rough and bumpy.
I am really upset; why did a simple allergy lead to this? The doctor I consulted did not provide me with a clear answer.
Now, I am afraid to apply any medication for fear of further redness and swelling.
What should I do now?

Māomī, 20~29 year old female. Ask Date: 2008/05/21

Dr. Hong Zhengsheng reply Dermatology


Hello, cat owner: The best advice is to "find a dermatologist you trust and schedule an appointment." I recommend that when your cat exhibits the described symptoms, you should promptly visit a public hospital in your city or county and consult with a dermatologist.
All our physicians are very willing to assist you.
Thank you for using "Taiwan e-Hospital" to ask your questions.
"Taiwan e-Hospital" cares about your health.

Reply Date: 2008/05/21

More Info


It sounds like you are experiencing a challenging situation with your skin after using an allergy cream, specifically Comybor cream, which contains antifungal components. The development of small bumps and inflammation on your cheeks after using this cream can be quite distressing, especially when you were initially seeking treatment for redness caused by improper use of alpha hydroxy acids (AHAs).

First, let's clarify the potential reasons behind your skin reaction. The use of topical medications, especially those containing active ingredients like antifungals or corticosteroids, can sometimes lead to unexpected side effects. In your case, the Comybor cream may have disrupted your skin's natural barrier or altered the balance of microorganisms on your skin, leading to an inflammatory response that manifests as acne-like bumps or pustules. This condition is often referred to as "perioral dermatitis" or "steroid-induced acne," depending on the specific context and ingredients involved.

When you applied the cream, it is possible that your skin was already compromised due to the previous irritation from the AHAs. This could have made your skin more susceptible to irritation or allergic reactions from the new medication. Additionally, antifungal creams can sometimes cause irritation or allergic reactions in sensitive individuals, leading to the symptoms you described.

The fact that your doctor later diagnosed you with acne suggests that the bumps you are experiencing may not be directly caused by the Comybor cream itself but rather a secondary reaction. Acne can be exacerbated by various factors, including hormonal changes, stress, and the use of certain topical products. In some cases, the use of heavy creams or ointments can clog pores, leading to breakouts.

Given your situation, here are some recommendations:
1. Discontinue Use of Irritating Products: Since you have already experienced adverse reactions, it is wise to stop using any products that may irritate your skin further, including the Comybor cream and any other topical medications that have not been prescribed specifically for your current condition.

2. Consult a Dermatologist: If you haven't already, consider seeking a second opinion from a dermatologist who can provide a thorough examination of your skin and recommend appropriate treatments. They may suggest topical treatments that are non-comedogenic (won't clog pores) and suitable for your skin type.

3. Gentle Skincare Routine: Focus on a gentle skincare routine that includes a mild cleanser and a non-comedogenic moisturizer. Avoid using harsh scrubs or exfoliants, as these can further irritate your skin.

4. Topical Treatments: If your skin is still inflamed, your dermatologist may prescribe topical treatments such as benzoyl peroxide or salicylic acid, which can help reduce acne. In some cases, they may also recommend topical antibiotics if there is a bacterial component to your skin condition.

5. Monitor Your Skin: Keep track of any changes in your skin's condition. If you notice worsening symptoms or new reactions, inform your healthcare provider immediately.

6. Avoid Picking or Squeezing: It can be tempting to pick at bumps or inflamed areas, but this can lead to further irritation, scarring, or infection.

7. Consider Lifestyle Factors: Evaluate your diet, stress levels, and skincare habits. Sometimes, lifestyle changes can significantly impact skin health.

In summary, while it is understandable to feel frustrated and confused about your skin's reaction to the allergy cream, it is essential to approach the situation with care. By discontinuing the use of potentially irritating products, consulting a dermatologist, and adopting a gentle skincare routine, you can work towards restoring your skin's health. Remember, patience is key, as it may take time for your skin to heal and return to its normal state.

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