Numbness and Weakness: Possible Neurological Disorders - Neurology

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Numbness in the limbs and face?


Initially, there was severe bloating and irregular bowel movements, with increased frequency.
About two months later, there was numbness in both legs, itching on the soles of the feet, like being bitten by ants.
Subsequently, both legs became numb and weak.
A week later, there was weakness and numbness in both hands.
Another week later, there was difficulty breathing and swallowing, increased gastrointestinal motility, and involuntary muscle contractions throughout the body and gastrointestinal tract.
Since yesterday, there has been facial numbness and swelling of the lymph nodes on the right side of the neck.
Five days ago, there were sudden feelings of dizziness and fatigue.
Yesterday, the heart rate increased from 70 beats per minute to 90 beats per minute.
Could this be neuropathy or Guillain-Barré syndrome (GBS)?

Ge Mi, 30~39 year old female. Ask Date: 2009/03/03

Dr. Ye Boshou reply Neurology


Hello: The symptoms are very similar to Guillain-Barré Syndrome (GBS).
Please see a neurologist for an examination as soon as possible.

Reply Date: 2009/03/03

More Info


The symptoms you are describing—numbness and weakness in the legs and arms, difficulty breathing and swallowing, gastrointestinal issues, and facial numbness—are concerning and could potentially be indicative of several neurological disorders, including Guillain-Barré Syndrome (GBS) or other conditions affecting the nervous system.

Guillain-Barré Syndrome is an autoimmune disorder where the body's immune system mistakenly attacks the peripheral nerves. It often begins with weakness and tingling in the legs, which can progress to more severe muscle weakness and paralysis. The symptoms can develop rapidly, sometimes within days or weeks, and may include difficulty with eye movement, facial expressions, and swallowing, as well as respiratory difficulties. The fact that you are experiencing numbness and weakness in both legs and arms, along with respiratory issues, raises the possibility of GBS.

Another condition to consider is myasthenia gravis, which is characterized by weakness and rapid fatigue of voluntary muscles. This condition can also lead to difficulties in swallowing and breathing, as well as muscle weakness that may fluctuate throughout the day.
Your symptoms of gastrointestinal issues, such as increased bowel movements and abdominal discomfort, could also be related to a neurological condition, as the autonomic nervous system controls involuntary bodily functions, including digestion. The sensation of your legs and arms feeling like they are "asleep" or "tingling" can be attributed to nerve compression or damage, which can occur in various neurological disorders.

The enlargement of the lymph nodes in your neck could suggest an underlying infection or inflammatory process, which may or may not be related to your neurological symptoms. It is essential to consider the entire clinical picture, including any recent infections, vaccinations, or illnesses, as these can sometimes trigger or exacerbate autoimmune responses.

Given the complexity and potential severity of your symptoms, it is crucial to seek immediate medical attention. A neurologist can perform a thorough evaluation, which may include blood tests, imaging studies (such as MRI or CT scans), and possibly a lumbar puncture to analyze cerebrospinal fluid. These tests can help determine the underlying cause of your symptoms and guide appropriate treatment.

In summary, while Guillain-Barré Syndrome is a strong possibility given your symptoms, other neurological disorders could also be at play. It is vital to consult with a healthcare professional as soon as possible to receive a proper diagnosis and treatment plan. Early intervention can significantly impact the outcome and recovery in cases of neurological disorders.

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