Is Nicotine Replacement Therapy Effective for Quitting Smoking? - Smoking Cessation

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Is nicotine replacement therapy effective for quitting smoking? Are there any side effects?

A-Jia, 20~29 year old female. Ask Date: 2009/04/28

Dr. Cai Fushun reply Smoking Cessation


Hello: In response to your question, the benefits of using Nicotine Replacement Therapy (NRT) include alleviating nicotine withdrawal symptoms, reducing the discomfort of quitting smoking, and preventing smokers from being exposed to carcinogens and other harmful toxins.
Methods of NRT include nicotine patches, gum, and nasal sprays, with a success rate of 15-20% over six months.
The side effects of nicotine patches can include skin allergies (25-50%), diarrhea, indigestion, musculoskeletal pain (3-9%), and insomnia (1-3%).
The side effects of nicotine gum may include a bitter taste, belching, bloating, nausea, and jaw pain.

Reply Date: 2009/04/28

More Info


Nicotine Replacement Therapy (NRT) has been widely recognized as an effective method for helping individuals quit smoking. The primary goal of NRT is to alleviate withdrawal symptoms and cravings associated with nicotine addiction, thereby making the cessation process more manageable. Various forms of NRT are available, including nicotine patches, gum, lozenges, nasal sprays, and inhalers. Research indicates that NRT can increase the chances of successfully quitting smoking by approximately 15-20% when used correctly.

The effectiveness of NRT lies in its ability to provide a controlled dose of nicotine without the harmful tar and toxic substances found in cigarettes. By delivering nicotine in a less harmful way, NRT helps to reduce withdrawal symptoms such as irritability, anxiety, and cravings, which are common challenges faced by individuals trying to quit smoking. This can lead to a more positive experience during the quitting process, increasing the likelihood of long-term success.

However, like any medical intervention, NRT is not without its potential side effects. The side effects can vary depending on the form of NRT used. For instance, nicotine patches may cause skin irritation or allergic reactions in some users, with reports indicating that 25-50% of users experience some form of skin reaction. Other common side effects associated with nicotine patches include gastrointestinal issues such as diarrhea and indigestion, musculoskeletal pain, and sleep disturbances, with insomnia reported in about 1-3% of users.

Nicotine gum and lozenges also have their own set of side effects, which may include a bitter taste, hiccups, bloating, nausea, and jaw discomfort. These side effects can be bothersome but are generally mild compared to the health risks associated with continued smoking.

It is essential for individuals considering NRT to consult with healthcare professionals to determine the most appropriate form of therapy based on their specific needs and medical history. For example, individuals with certain pre-existing conditions or those taking specific medications may need to approach NRT with caution.

In summary, Nicotine Replacement Therapy is an effective tool for quitting smoking, with a range of options available to suit different preferences. While it does come with potential side effects, these are generally manageable and far less severe than the consequences of continued tobacco use. For those struggling with nicotine addiction, NRT can provide a valuable support system in their journey toward a smoke-free life. It is advisable to combine NRT with behavioral therapies and support groups for the best chance of success, as these approaches can address the psychological aspects of addiction and help individuals develop healthier coping strategies.

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