Can I Get the HPV Vaccine if I Have Uterine Fibroids? - Obstetrics and Gynecology

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Uterine fibroids


Hello, six months ago, I visited a gynecologist due to irregular menstruation and learned that I have uterine fibroids.
In this situation, is it still possible to receive the cervical cancer vaccine?

COCO, 20~29 year old female. Ask Date: 2009/03/23

Dr. Yang Wangjun reply Obstetrics and Gynecology


Hello: The cervical cancer vaccines currently available are the quadrivalent Gardasil (targeting human papillomavirus types 6, 11, 16, and 18) and the bivalent Cervarix (targeting human papillomavirus types 16 and 18).
Gardasil is recommended for administration to individuals aged 9 to 26 years, while Cervarix is recommended for those aged 10 to 25 years.
Both vaccines contain antigens derived from the outer capsid proteins of the human papillomavirus and do not include the core DNA genetic material.
Currently, there are no research reports indicating that receiving the cervical cancer vaccine causes worsening or improvement of uterine fibroids.
Theoretically, there is no connection between uterine fibroids and the cervical cancer vaccine.
Thank you for your inquiry!

Reply Date: 2009/03/23

More Info


Yes, you can receive the HPV vaccine even if you have uterine fibroids. Uterine fibroids, which are benign tumors of the uterus, do not interfere with the effectiveness or safety of the HPV vaccine. The HPV vaccine is designed to protect against certain strains of the human papillomavirus that can lead to cervical cancer and other HPV-related diseases.
It is important to understand that the presence of uterine fibroids does not increase your risk of HPV infection or cervical cancer. However, if you have any concerns about your health or the fibroids, it is always a good idea to discuss them with your healthcare provider before getting vaccinated. They can provide personalized advice based on your medical history and current health status.

The HPV vaccine is recommended for preteens and young adults, but it can be given to individuals up to the age of 45. The vaccine works best when given before the onset of sexual activity, but it is still beneficial for those who are already sexually active, as it can protect against strains of HPV that they may not have been exposed to yet.

In terms of the vaccine's mechanism, it helps the immune system recognize and fight off the HPV virus if exposed in the future. This is crucial because certain high-risk types of HPV are known to cause cervical cancer, as well as other cancers like anal, vulvar, and oropharyngeal cancers. The vaccine does not treat existing HPV infections or related diseases, but it can prevent new infections.

If you are experiencing symptoms related to your fibroids, such as heavy menstrual bleeding or pelvic pain, it is essential to address those issues with your healthcare provider. They can help determine the best course of action for managing your fibroids, which may include monitoring, medication, or surgical options, depending on the severity of your symptoms and the size of the fibroids.

In summary, having uterine fibroids does not prevent you from receiving the HPV vaccine. It is a safe and effective way to protect against HPV-related diseases, and discussing any concerns with your healthcare provider can help ensure that you make informed decisions about your health. Regular screenings, such as Pap smears, are also important for monitoring cervical health, especially if you have a history of abnormal results or other risk factors.

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