Fibrosis in Urology: Causes, Symptoms, and Concerns - Urology

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Fibrosis?


I would like to ask the doctor what causes localized white membrane fibrosis? I actually just discovered it not long ago; it looks like an hourglass and feels strange.
What are the clinical symptoms? Could you please list a few for reference? I found some information later that mentioned acquired penile deformity—"hourglass (or constrictive) deformity." Is there any relation to this?
Additionally, I have noticed "blood lines" on both sides of my scrotum, but they are not painful.
Initially, there was only one on the left side, but now it seems like there are three, and the right side has two as well.
Referring to this photo http://www.flickr.com/photos/emilychiavelli/2738209010/sizes/l/, it looks like that scar but is thinner and longer, with a dark red color.
The key point is that it is indented inward, while the epidermis appears similar to a regular scar with some horizontal lines.
The areas without blood lines are normal skin.
I have not experienced any discomfort (or perhaps I am unaware of it), so I only noticed it by chance.
I would like to ask the doctor what this could be.
Thank you for your assistance.

Xiao Yu, 20~29 year old female. Ask Date: 2009/04/06

Dr. Xu Weikai reply Urology


Xiao Yu: Hello, fibrosis occurs due to factors such as trauma or infection, which causes the white membrane to become thicker during the healing process.
When scarring occurs, it can lead to constriction, resulting in a localized reduction in penile size.
However, this is not always the case.
If symptoms persist or worsen, it may indicate other issues, such as certain soft tissue disorders like Peyronie's disease, or the presence of tumors, which cannot be diagnosed online.
As for scarring, it cannot be diagnosed without a physical examination.
If there are any unclear points, feel free to ask again for further discussion and research.
Sincerely, Dr.
Hsu Wei-Kai, Director of Urology, Taitung Hospital, Department of Health, Executive Yuan.

Reply Date: 2009/04/06

More Info


Fibrosis in urology, particularly when it involves the penis, can be a complex condition with various underlying causes and implications. The term "fibrosis" generally refers to the thickening and scarring of connective tissue, which can occur in various parts of the body, including the urogenital system. In the context of urology, one of the most recognized forms of fibrosis is Peyronie's disease, which is characterized by the formation of fibrous plaques in the tunica albuginea of the penis, leading to curvature and deformity during erections.


Causes of Fibrosis
1. Trauma or Injury: One of the most common causes of penile fibrosis is trauma. This can occur during sexual activity or due to accidents that cause injury to the penis. The body responds to this injury by forming scar tissue, which can lead to the characteristic curvature associated with Peyronie's disease.

2. Genetic Factors: Some individuals may have a genetic predisposition to developing fibrosis. Certain hereditary conditions can increase the likelihood of connective tissue disorders, which may manifest as fibrosis in the penis.

3. Chronic Inflammation: Conditions that cause chronic inflammation in the genital area can also lead to fibrosis. This includes infections or inflammatory diseases that affect the urogenital tract.

4. Age: As men age, the risk of developing conditions like Peyronie's disease increases. The natural aging process can lead to changes in the connective tissue, making it more susceptible to fibrosis.

5. Medical Conditions: Certain medical conditions, such as diabetes, hypertension, and Dupuytren's contracture (a condition that causes thickening of the tissue in the hand), have been associated with an increased risk of developing penile fibrosis.


Symptoms of Fibrosis
The symptoms of fibrosis in the urogenital area can vary depending on the severity and location of the fibrotic tissue. Common symptoms may include:
1. Curvature of the Penis: This is often the most noticeable symptom, particularly during erections. The curvature can be upward, downward, or lateral, depending on where the fibrous tissue has formed.

2. Pain: Some individuals may experience pain during erections or sexual activity, especially if the fibrotic tissue is extensive.

3. Changes in Size or Shape: The penis may appear shorter or have an irregular shape due to the presence of fibrous plaques.

4. Difficulty with Erections: In some cases, fibrosis can lead to erectile dysfunction, as the fibrous tissue may interfere with the normal expansion of the erectile tissue.

5. Palpable Plaques: In some cases, individuals may be able to feel the fibrous plaques beneath the skin of the penis.


Concerns Regarding "Blood Stripes" on the Scrotum
The appearance of "blood stripes" or dark red lines on the scrotum can be concerning, but it is essential to consider several factors:
1. Vascular Changes: The dark red lines may represent superficial blood vessels that have become more prominent, possibly due to increased blood flow or vascular changes in the area. This can occur due to various reasons, including physical activity or changes in temperature.

2. Dermatological Conditions: Certain skin conditions can cause changes in the appearance of the skin on the scrotum, including pigmentation changes or the formation of vascular lesions.

3. Injury or Trauma: If there has been any recent trauma to the area, it could lead to the formation of bruising or vascular changes.

4. Infection or Inflammation: Although you mentioned no pain or discomfort, it is still possible for infections or inflammatory conditions to cause changes in the skin's appearance.


Recommendations
Given the complexity of your symptoms and concerns, it is crucial to consult with a urologist who can perform a thorough examination and possibly recommend imaging studies or other diagnostic tests. They can help determine the exact nature of the fibrosis and any associated conditions, such as Peyronie's disease or other urological issues. Additionally, if the appearance of the "blood stripes" changes or if you develop any new symptoms, it is essential to seek medical attention promptly.

In conclusion, understanding fibrosis in urology involves recognizing its potential causes, symptoms, and implications. It is essential to approach this condition with a comprehensive evaluation to ensure appropriate management and treatment.

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