Rare acidosis
Dear Dr.
Lin,
I am a new mother, and my baby was born on April 17 at the Hsin-Lou Hospital in Tainan.
Our family is very anxious because the hospital has asked us to come back for a re-examination.
Although we haven't gone for the re-examination yet, the hospital has scheduled us for blood tests on the 27th and 28th.
I am really worried about my baby's health, so I would like to ask Dr.
Lin what the standard values are for rare metabolic acidosis.
What is the threshold for exceeding the standard values, and what are the indices for not meeting the standard values? What should I do for psychological defense in the meantime? Should I wait for the test results to come out? Could you please provide me with some guidance? Thank you!
Concerned Mommy
Xinshou Mama, 30~39 year old female. Ask Date: 2009/05/06
Dr. Lin Xiujuan reply Rare Disease
Hello: Due to the need to return to the original birth hospital for a re-examination of the blood sample, the value range is usually in the context of a false positive.
The meaning of "false positive" in screening indicates that the concentration of certain metabolites in the newborn's blood is elevated and requires further testing to confirm whether there is a persistent elevation or abnormality.
When you receive a notification that the newborn screening result is a false positive, please do not be overly anxious.
Just follow the instructions and go to the original birth hospital for a blood re-test as per the contact information provided.
Once the re-test blood report is available, based on the significance of the re-test values, if further diagnosis and treatment at a designated referral hospital are necessary, dedicated personnel will contact you, so there is no need to worry excessively.
Tainan Hsin-Lou Hospital is under the Health Foundation, and mothers can check their child's report online about two weeks after the blood test.
The report inquiry website is: http://www.cfoh.org.tw.
Personal area: Enter the mother's name and ID number.
The newborn screening announcement includes eleven test items, among which those related to acidemia include Methylmalonic Acidemia Type I, Isovalerylic Acidemia, and Propionic Acidemia.
Reply Date: 2009/05/06
More Info
Understanding rare metabolic disorders, such as acidosis, can be overwhelming for new parents, especially when faced with the uncertainty of a potential diagnosis. It’s completely natural to feel anxious when your newborn is undergoing further testing. Here’s a comprehensive overview of what you need to know about rare acidosis, its implications, and how to navigate this challenging time.
What is Acidosis?
Acidosis refers to an excess of acid in the body fluids, which can disrupt the normal pH balance. It can be classified into two main types: metabolic acidosis and respiratory acidosis. Metabolic acidosis occurs when the body produces too much acid or when the kidneys are not removing enough acid from the body. Respiratory acidosis is due to the lungs not being able to remove enough carbon dioxide, leading to increased acidity.
Standard Values and Testing
The standard pH range for human blood is typically between 7.35 and 7.45. A pH below 7.35 indicates acidosis, while a pH above 7.45 indicates alkalosis. When it comes to metabolic acidosis, the bicarbonate (HCO3-) levels are also crucial. Normal bicarbonate levels range from 22 to 28 mEq/L. Levels below this range can indicate metabolic acidosis.
In newborns, the interpretation of these values can be more complex due to their developing physiology. Therefore, it’s essential to consult with a pediatrician or a specialist who can provide context to the results based on your baby’s overall health and clinical presentation.
Psychological Preparedness
While waiting for test results, it’s important to manage your anxiety. Here are some strategies:
1. Stay Informed: Understanding the condition can help alleviate fears. Research reputable sources about acidosis and its implications.
2. Talk to Professionals: Don’t hesitate to reach out to your healthcare provider with questions. They can provide clarity on what the tests entail and what the potential outcomes might mean for your baby.
3. Connect with Support Groups: Engaging with other parents who have faced similar situations can provide emotional support and practical advice.
4. Practice Self-Care: Ensure you are taking care of your own mental health. This can include mindfulness practices, exercise, or simply taking time to relax.
What to Expect After Testing
Once the tests are conducted, results typically take a few days to process. During this time, it’s crucial to remain calm and patient. If acidosis is confirmed, the treatment will depend on the underlying cause. Treatment options may include:
- Hydration: Ensuring your baby is well-hydrated can help balance pH levels.
- Bicarbonate Therapy: In some cases, sodium bicarbonate may be administered to help neutralize the acidity.
- Dietary Adjustments: Depending on the specific metabolic disorder, dietary changes may be necessary to manage acid levels.
Conclusion
As a new parent, facing the possibility of a rare metabolic disorder can be daunting. However, understanding the condition, knowing the standard values for acidosis, and preparing psychologically can help you navigate this challenging time. Remember, the healthcare team is there to support you and your baby, so don’t hesitate to reach out for guidance and reassurance. Once the test results are in, you will have a clearer picture of your baby’s health and the next steps to take.
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