HPV and Its Risks: Insights on Urethral Warts - Urology

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Genital warts in the urethra?


In October 2008, I had unprotected oral sex and protected vaginal intercourse with my girlfriend, whom I had known for three months.
What is the likelihood of contracting HPV? I have undergone two HPV DNA tests (both high-risk and low-risk) which returned negative results, one at one month and another at nine months after exposure.
It has been over ten months now without any lesions.
How long can I completely rule out the infection? I am very worried.

Also, I would like to ask if it is possible for genital warts to only develop deep within the urethra while the mucosa near the urethral opening remains unaffected.
Have you encountered such cases before? I appreciate your clarification.
Thank you!

JJ, 20~29 year old female. Ask Date: 2009/06/18

Dr. Xu Weikai reply Urology


JJ: Hello, cauliflower can grow on any mucosal surface, including the urethra.
After 10 months, if no lesions are observed, it is advisable to examine the bladder.
Generally, a cystoscopy is recommended.
If any lesions are found, a specialized electrosurgical device can be used for excision and cauterization.
This will help rule out deep urethral or bladder lesions.
Clinically, I have encountered cauliflower lesions in the bladder.
Good luck, and if you have any further questions, feel free to ask, and we can discuss and research together.
Department of Urology, Taitung Hospital, Ministry of Health and Welfare, Director Xu Weikai.

Reply Date: 2009/06/18

More Info


Understanding HPV (Human Papillomavirus) and its associated risks is crucial for both men and women, especially when it comes to sexual health. HPV is a common sexually transmitted infection, with over 100 types identified, of which around 40 can infect the genital area. Among these, certain strains are classified as high-risk due to their association with various cancers, including cervical, anal, and oropharyngeal cancers. Low-risk types, such as HPV 6 and 11, are primarily associated with benign conditions like genital warts (also known as "cauliflower" warts).

In your case, you mentioned engaging in oral sex without a condom and vaginal intercourse with a condom. While using a condom significantly reduces the risk of HPV transmission, it does not eliminate it entirely, especially for oral sex where the virus can still be transmitted through skin-to-skin contact. The risk of contracting HPV from a partner who may be infected is present, particularly if they have high-risk strains or visible warts.

You have undergone two HPV DNA tests, both returning negative results for high-risk and low-risk types. This is a positive indication, as it suggests that you are not currently infected with HPV. However, it is important to note that HPV can sometimes remain dormant for years, meaning that even if you test negative now, it does not guarantee that you were never exposed to the virus. The immune system often clears HPV infections naturally within two years, but this can vary from person to person.

Regarding your concern about the possibility of warts developing only in the deeper parts of the urethra, it is indeed possible for HPV to cause lesions that are not immediately visible. Warts can develop in areas that are not easily examined, including the urethra. If you have not experienced any symptoms such as itching, pain, or unusual discharge, it is a good sign, but it does not completely rule out the presence of HPV.

To address your worries about the timeline for clearing the virus, while many individuals clear the virus within two years, some may take longer. Regular follow-ups with your healthcare provider are essential for monitoring your health. If you have concerns about potential symptoms or the risk of warts, consider consulting a urologist or a specialist in sexual health. They can perform a thorough examination and may recommend further testing if necessary.

In summary, while your current negative HPV tests are reassuring, it is important to remain vigilant about your sexual health. Practicing safe sex, including the use of condoms and regular screenings, can help reduce your risk of HPV and other sexually transmitted infections. Additionally, consider discussing the HPV vaccine with your healthcare provider, as it can provide protection against the most common high-risk strains of the virus. Regular check-ups and open communication with your partner about sexual health are also key components in managing HPV risks effectively.

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