the Use of Jing An Ning in Depression Treatment - Psychiatry

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Jing Anning


Is the medication used for "depression" or is it for patients who are already taking medication for "depression"? Is a dosage of 0.25 considered serious in this situation?

Xiao Ji, 20~29 year old female. Ask Date: 2009/08/18

Dr. Li Zhengfeng reply Psychiatry


Hello: First, thank you for your letter.
Jing An Ning is a central nervous system depressant primarily used for the treatment of anxiety disorders or for short-term relief of anxiety symptoms.
It can also serve as an adjunctive treatment for anxiety and panic disorders associated with depression and restlessness.
The recommended dosage is approximately 1.2 mg to 2.4 mg.
Thank you.

Reply Date: 2009/08/18

More Info


Jing An Ning, known generically as amisulpride, is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and, in some cases, major depressive disorder (MDD). It works by modulating the levels of certain neurotransmitters in the brain, particularly dopamine, which plays a crucial role in mood regulation. While it is not typically classified as a first-line treatment for depression, it may be prescribed as an adjunctive therapy for patients who have not responded adequately to standard antidepressants.

In the context of depression, amisulpride can be beneficial for patients who experience significant depressive symptoms, particularly those with psychotic features or treatment-resistant depression. The medication may help alleviate symptoms such as low mood, lack of motivation, and anhedonia (the inability to feel pleasure). However, it is essential to note that amisulpride is not a traditional antidepressant; its primary indication is for psychotic disorders.

Regarding the dosage of 0.25 mg, it is important to clarify that this is an unusually low dose for amisulpride, as typical dosages range from 400 mg to 1200 mg per day, depending on the condition being treated. If you are indeed taking 0.25 mg, it is crucial to discuss this with your healthcare provider, as it may not be an effective dose for managing your symptoms. The severity of your condition and the appropriateness of the dosage should be evaluated by a qualified medical professional.

As for the potential side effects of amisulpride, they can include sedation, weight gain, and extrapyramidal symptoms (movement disorders), among others. Some patients may experience an increase in anxiety or agitation, especially during the initial stages of treatment. It is also important to monitor for any signs of worsening depression or suicidal thoughts, as these can occur with any antidepressant or antipsychotic medication.

If you are concerned about the severity of your depression or the appropriateness of your treatment with Jing An Ning, it is vital to maintain open communication with your healthcare provider. They can assess your symptoms, review your medication regimen, and make necessary adjustments to ensure you receive the most effective treatment for your condition. Additionally, combining medication with psychotherapy or other supportive therapies can enhance treatment outcomes and provide a more comprehensive approach to managing depression.

In summary, Jing An Ning (amisulpride) can be used in the treatment of depression, particularly in cases where other treatments have failed. However, the dosage and potential side effects should be closely monitored by a healthcare professional. If you have concerns about your treatment or the severity of your symptoms, do not hesitate to reach out to your doctor for further evaluation and guidance.

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