Hepatitis B: Do I Have the Virus? - Gastroenterology and Hepatology

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Dear Doctor: I tested positive for hepatitis B surface antigen and positive for surface antibodies on August 14 at the municipal hospital.
Then, on September 21, I tested negative for hepatitis B surface antigen and positive for surface antibodies at Chimei Hospital.
Do I have hepatitis B? Thank you for your answer.

Azi, 30~39 year old female. Ask Date: 2009/10/05

Dr. You Ligang reply Gastroenterology and Hepatology


Hello, this indicates that you have had hepatitis B, and the spontaneous loss of surface antibodies means that you have developed antibodies, providing you with immunity against the hepatitis B virus.
Wishing you good health.
Dr.
You Li-Guang, Taoyuan Hospital, Department of Health.

Reply Date: 2009/10/05

More Info


Based on your inquiry regarding your Hepatitis B (HBV) test results, it appears that you have undergone two separate tests with differing outcomes. The first test on August 14 indicated that both the Hepatitis B surface antigen (HBsAg) and the Hepatitis B surface antibody (anti-HBs) were positive. However, the second test on September 21 showed that the HBsAg was negative while the anti-HBs remained positive.
To clarify, the presence of HBsAg indicates an active Hepatitis B infection, either acute or chronic. Conversely, the presence of anti-HBs suggests that you have developed immunity to the virus, either through past infection or vaccination. In your case, the first test showing both HBsAg and anti-HBs positive could suggest that you were either in the process of clearing an infection or that there was a transient phase of infection where both markers were present.

The subsequent test showing a negative HBsAg result is significant. It indicates that you no longer have an active Hepatitis B infection. The positive anti-HBs result suggests that your immune system has responded effectively, producing antibodies that protect you from future infections. This is a desirable outcome, as it means you are likely immune to Hepatitis B.

In summary, based on the most recent test results, you do not have Hepatitis B. The presence of anti-HBs indicates that you have immunity, which is a positive development. However, it is essential to understand that while you are currently immune, it is still advisable to monitor your health and maintain regular check-ups, especially if you have any risk factors for Hepatitis B or other liver diseases.

To further elaborate, Hepatitis B can be transmitted through various means, including sexual contact, sharing needles, and from mother to child during childbirth. If you have not engaged in high-risk behaviors, the likelihood of contracting the virus again is low, especially since you have developed antibodies.

It's also worth noting that the levels of anti-HBs can decline over time, but this does not necessarily mean you are at risk of infection again. Generally, if you have a sufficient level of anti-HBs (typically above 10 mIU/mL), you are considered protected against Hepatitis B.

In conclusion, based on your test results, you do not currently have Hepatitis B, and you have developed immunity against it. It is always wise to keep abreast of your health status and consult with your healthcare provider for personalized advice and any necessary follow-up tests.

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