Rectal Adenocarcinoma: Diagnosis, Treatment, and Care - Oncology

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Rectal adenocarcinoma


Dear Doctor,
Recently, an elder in my family visited the doctor due to blood in the stool, initially thinking it was caused by hemorrhoids (which they already have).
However, during the endoscopy, a polyp approximately 2 cm in size was found 4 cm from the anus, and upon biopsy, it was diagnosed as adenocarcinoma.
This sudden news has completely altered the atmosphere and daily life at home.
The hospital physician has initially classified it as T2N0M0, but we can't help but worry about the following:
1.
Is this classification definitive, or will a more accurate determination require surgical removal and further testing?
2.
If surgery is necessary, is it possible to opt for anal sphincter preservation?
3.
Will chemotherapy be required after the surgery?
4.
How can we provide psychological support and care for the elder at home?

Rickey, 30~39 year old female. Ask Date: 2009/10/20

Dr. Chen Sirong reply Oncology


1.
Currently, pathological slides for malignant tumors require confirmation from two physicians, so the chance of error is extremely low.
After surgery, only the staging has changed; the physician predicts a clinical stage of T2N0M0, while the definitive pathological staging post-surgery will determine the exact stage of cancer.

2.
The proximity to the anus reduces the chances of preservation, so it is essential to consult with his physician.

3.
The postoperative pathological staging will determine the next steps.

4.
The success rate of the first treatment is nearly 100%, with the main concern being the possibility of recurrence in the future.
Given that your elder is at clinical stage I, the likelihood of recurrence should be quite low.
Therefore, he can live well without unnecessary worry; the earliest concern about recurrence can wait until that year.
The five-year survival rate for patients with stage I colorectal cancer can reach over 90%, while stage II is about 70%, and stage III is around 50%.
In contrast, patients with stage IV have a poorer prognosis.
Dr.
Chen Sih-Rong, Taoyuan.

Reply Date: 2009/10/20

More Info


Understanding rectal adenocarcinoma, particularly in the context of your family member's recent diagnosis, can be daunting and emotionally challenging. Here, I will address your questions based on the current medical understanding of this condition.

1. Diagnosis Confirmation: The initial staging of T2N0M0 indicates that the tumor is invasive (T2) but has not spread to nearby lymph nodes (N0) or distant sites (M0). While this is a preliminary assessment, the definitive staging often requires surgical intervention. During surgery, the tumor can be fully excised, and the pathology report will provide a more accurate assessment of the tumor's characteristics, including its depth of invasion and any potential lymphovascular invasion. Therefore, while the initial staging is helpful, it is essential to confirm the diagnosis and staging through surgical pathology.

2. Surgical Options and Anal Preservation: The possibility of preserving the anus during surgery largely depends on the tumor's location, size, and extent of invasion. In cases where the tumor is located low in the rectum, surgeons may perform a procedure called a low anterior resection, which can allow for anal preservation. However, if the tumor is too close to the anal sphincter or if there is a significant risk of incomplete resection, a more radical approach, such as an abdominoperineal resection (APR), may be necessary, which would involve removing the anus and creating a permanent colostomy. A thorough discussion with a colorectal surgeon will help clarify the best surgical approach for your family member.

3. Postoperative Chemotherapy: The need for chemotherapy after surgery depends on several factors, including the final pathology results, the tumor's grade, and whether there are any high-risk features (such as lymphovascular invasion or poorly differentiated histology). In cases of early-stage rectal cancer (like T2N0M0), adjuvant chemotherapy may not always be necessary. However, if there are concerns about the risk of recurrence, your oncologist may recommend chemotherapy or even radiation therapy as part of a multimodal treatment approach.

4. Psychological Support and Care: Supporting a family member diagnosed with cancer involves both emotional and practical aspects. Here are some strategies for providing care and psychological support:
- Open Communication: Encourage your family member to express their feelings and concerns. Listening without judgment can help them feel supported.

- Education: Understanding the diagnosis and treatment options can empower both the patient and the family. Attend medical appointments together, ask questions, and seek clarification on any uncertainties.

- Professional Support: Consider involving a mental health professional or counselor who specializes in oncology to help your family member cope with the emotional impact of their diagnosis.

- Practical Support: Assist with daily activities, transportation to appointments, and meal preparation. This can alleviate some stress and allow your family member to focus on their recovery.

- Support Groups: Encourage participation in support groups for cancer patients. Sharing experiences with others facing similar challenges can provide comfort and reduce feelings of isolation.

In summary, while the initial diagnosis of rectal adenocarcinoma can be overwhelming, understanding the steps involved in confirming the diagnosis, exploring surgical options, and considering postoperative care can help you and your family member navigate this journey. Engaging with healthcare professionals and providing emotional support will be crucial in this process.

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