Systemic lupus erythematosus (SLE)
Hello Doctor: Previously, my ANA test result was 1:160, and the attending physician believed that I do not have SLE, considering my facial rash to be seborrheic dermatitis.
Therefore, I have not continued follow-up or medication for nearly a year.
In the past two days, before the rain, I have noticeably felt pain in my right elbow joint, and today I also felt slight pain in the joint of my right middle finger.
Additionally, three days ago, I suddenly developed four to five ulcers in my mouth that have not healed since (oral ulcers occur frequently; the last time was a month ago, but there were only one or two at most).
Doctor, should I visit a rheumatologist again, or can I just apply oral ointment myself? Should I be concerned about the joint pain?
Xia, 20~29 year old female. Ask Date: 2009/11/13
Dr. Zeng Guosen reply Internal Medicine
Hello Summer: There are specific diagnostic criteria for systemic lupus erythematosus (SLE), and a positive antinuclear antibody (ANA) test alone does not confirm the diagnosis.
Recently, you have experienced oral ulcers and joint pain; please refrain from self-medicating and seek consultation with a rheumatologist.
Any pain or unusual symptoms in your body should be taken seriously, and you should seek medical assistance.
Thank you for your question!
Reply Date: 2009/11/13
More Info
Lupus, or systemic lupus erythematosus (SLE), is a complex autoimmune disease that can affect multiple organ systems in the body. It is characterized by periods of flares and remissions, and its symptoms can vary widely among individuals. The presence of antinuclear antibodies (ANA) is a common laboratory finding in lupus patients, but a positive ANA test alone is not sufficient for a diagnosis of SLE. Other clinical criteria must be met, including specific symptoms such as joint pain, skin rashes, and oral ulcers.
In your case, you mentioned that your ANA test was previously at a titer of 1:160, which is considered low and may not be indicative of lupus on its own. However, the development of new symptoms, such as joint pain in the right elbow and middle finger, as well as multiple oral ulcers, raises concerns that warrant further evaluation. Joint pain, especially when it is persistent or worsening, can be a sign of an underlying autoimmune condition, including lupus or other types of inflammatory arthritis.
The presence of oral ulcers is also significant. While they can occur in various conditions, recurrent oral ulcers are often associated with autoimmune diseases, including lupus. The fact that you have experienced multiple ulcers simultaneously is noteworthy and should not be overlooked.
Given these new symptoms, it would be prudent to seek further medical advice from a rheumatologist, especially since you have a history of possible lupus-related symptoms. A rheumatologist can perform a comprehensive evaluation, which may include a detailed history, physical examination, and additional laboratory tests to assess for lupus or other autoimmune conditions. They can also help determine whether your current symptoms are related to a flare of lupus or another condition altogether.
In the meantime, while you may consider using topical medications for the oral ulcers, it is essential to address the joint pain as well. Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) may provide temporary relief for joint discomfort, but they do not address the underlying cause. Therefore, it is advisable not to rely solely on self-treatment without consulting a healthcare professional.
In summary, the combination of joint pain and recurrent oral ulcers, especially in the context of a previous ANA test, suggests that further evaluation is warranted. It is essential to take these symptoms seriously and consult a rheumatologist for a thorough assessment. Early intervention can lead to better management of potential autoimmune conditions and improve your overall quality of life.
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