Red Spots on the Lower Leg: Possible Causes and Next Steps - Internal Medicine

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Erythema on the lower leg?


During middle school, I developed small red spots near the outer side of my ankle and close to the hip area, about the size of a fingernail.
Initially, they were slightly tender, and over time, the color deepened and became more pronounced, resembling strawberries.
They were neither painful nor itchy, and I didn't pay much attention to them for several years.
Recently, I noticed similar red spots appearing on my calves.
Could this be lupus erythematosus or erythema nodosum? I have a tendency to have a fast heartbeat and slightly elevated body temperature.
Could the red spots be related to any heart issues? What aspects should I investigate further, and what tests should I undergo?

Wu Yu, 10~19 year old female. Ask Date: 2009/12/04

Dr. Zeng Guosen reply Internal Medicine


Dear user: Based on your description, it is not possible to determine whether it is lupus erythematosus or erythema nodosum.
More information is needed to diagnose these conditions.
I recommend that you consult a dermatologist or a rheumatologist.
Please do not ignore this issue.
Thank you for your question!

Reply Date: 2009/12/04

More Info


When it comes to understanding red spots on the lower leg, particularly those that have been present for an extended period and have recently reappeared, there are several potential causes to consider. Based on your description, the red spots near your ankle and hip that initially presented with tenderness and later changed color could be indicative of a few dermatological or systemic conditions.

1. Erythema Nodosum: This condition is characterized by painful, red nodules that typically appear on the lower legs. They can be associated with various underlying conditions, including infections, medications, or systemic diseases. The fact that your spots are painless and have changed color over time may suggest a different condition, but it’s worth considering.

2. Lupus Erythematosus: The mention of "red spots" and the concern about lupus is significant. Lupus can cause a variety of skin manifestations, including rashes and lesions that may appear as red spots. However, lupus is also associated with systemic symptoms, so it would be essential to evaluate any other symptoms you may have, such as joint pain, fatigue, or fever.

3. Petechiae or Purpura: These are small red or purple spots that can occur due to bleeding under the skin. They can be caused by various factors, including infections, blood disorders, or even certain medications. If the spots are not raised and do not blanch when pressed, they may fall into this category.

4. Vascular Issues: Given your mention of a fast heartbeat and elevated body temperature, it’s important to consider whether there could be an underlying vascular issue. Conditions such as vasculitis can lead to skin changes and may require further investigation.

5. Allergic Reactions or Dermatitis: Sometimes, skin reactions can be due to contact dermatitis from allergens or irritants. If you’ve been exposed to new products or environments, this could be a potential cause.


Next Steps for Evaluation
Given the complexity of your symptoms and the potential for various underlying conditions, it is advisable to take the following steps:
1. Consult a Dermatologist: A specialist can provide a thorough examination of your skin lesions and may perform a skin biopsy if necessary to determine the exact nature of the spots.

2. Blood Tests: Comprehensive blood tests can help rule out systemic conditions such as lupus or other autoimmune disorders. Tests may include a complete blood count (CBC), inflammatory markers (like ESR or CRP), and specific autoimmune panels.

3. Monitor Symptoms: Keep track of any additional symptoms that may arise, such as joint pain, fatigue, or changes in your overall health. This information can be crucial for your healthcare provider.

4. Consider a Rheumatology Consultation: If there is a suspicion of an autoimmune condition, a referral to a rheumatologist may be warranted for further evaluation.

5. Lifestyle and Environmental Factors: Reflect on any recent changes in your lifestyle, diet, or environment that could have contributed to the appearance of these spots.

In conclusion, while the red spots on your lower leg could be benign, their persistence and recent reappearance warrant a thorough evaluation to rule out any serious underlying conditions. Early diagnosis and intervention can be crucial in managing any potential health issues effectively. Always consult with a healthcare professional for personalized advice and treatment options.

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