Gastrointestinal Sensation Loss and Sleep Issues - Neurology

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Gastrointestinal insensitivity and shallow sleep?


Three weeks ago, I took painkillers, muscle relaxants, and gout medication for foot pain due to gout.
After taking these medications continuously for three days, I stopped and noticed that I have lost gastrointestinal sensation, lack of appetite, and do not feel full after eating.
However, my bowel movements are normal, but I feel like my food is not fully digested.
I also experience shallow sleep and do not feel tired despite my body being fatigued.
This situation has persisted for a week.
Could this indicate nerve damage, or what kind of tests should I undergo? Thank you.

graylime, 20~29 year old female. Ask Date: 2010/02/10

Dr. Lin Zijing reply Neurology


In general, pain relievers and muscle relaxants do not cause the symptoms you mentioned.
It is advisable to consult the prescribing physician or a gastroenterologist for more clarity.

Reply Date: 2010/02/10

More Info


It sounds like you are experiencing a complex interplay of gastrointestinal issues and sleep disturbances, which can be quite distressing. Based on your description, it seems that after taking pain medications and muscle relaxants for gout, you have noticed a significant change in your gastrointestinal sensations, including a lack of hunger and a feeling of incomplete digestion. Additionally, your sleep quality has deteriorated, characterized by shallow sleep and a lack of perceived fatigue despite physical tiredness.

Firstly, it is important to understand that medications, especially those that affect the central nervous system (CNS), can have various side effects, including impacts on gastrointestinal function and sleep patterns. Muscle relaxants and certain pain medications can alter the way your body processes food and can affect the signals your brain receives regarding hunger and satiety. This could explain your loss of appetite and the sensation of not feeling full after eating.

The gastrointestinal system is closely linked to the nervous system, and disruptions in one can lead to issues in the other. The vagus nerve, which is part of the autonomic nervous system, plays a crucial role in regulating both gastrointestinal motility and the sleep-wake cycle. If there is any disruption in the nerve pathways or if the medications have caused any temporary changes in nerve function, this could lead to the symptoms you are experiencing.

Regarding your sleep issues, shallow sleep can be a result of various factors, including anxiety, stress, or even the medications you have taken. It is not uncommon for individuals to experience sleep disturbances after a change in medication or after taking drugs that affect the CNS. The feeling of not being able to feel tired despite physical fatigue may also be linked to disrupted sleep architecture, where the body does not cycle through the necessary stages of sleep effectively.

Given that these symptoms have persisted for a week, it would be prudent to consider a few steps:
1. Consult a Healthcare Professional: It is essential to discuss your symptoms with a healthcare provider, preferably one who specializes in gastroenterology or neurology. They can perform a thorough evaluation, including a review of your medication history, and may recommend tests to assess nerve function and gastrointestinal health.

2. Consider a Gastrointestinal Evaluation: Tests such as an upper endoscopy or gastric emptying study may be warranted to evaluate the function of your gastrointestinal tract and rule out any underlying conditions that may be contributing to your symptoms.

3. Monitor Your Diet: Keeping a food diary can help identify any potential triggers that may exacerbate your gastrointestinal symptoms. Eating smaller, more frequent meals may also help improve your digestion and appetite.

4. Sleep Hygiene Practices: Implementing good sleep hygiene can help improve your sleep quality. This includes maintaining a consistent sleep schedule, creating a restful environment, and avoiding stimulants close to bedtime.

5. Evaluate Medication Effects: If you suspect that your medications are contributing to your symptoms, discuss this with your healthcare provider. They may consider adjusting your medications or exploring alternatives that have fewer side effects on your gastrointestinal and sleep functions.

6. Stress Management: Since stress and anxiety can exacerbate both gastrointestinal and sleep issues, incorporating stress management techniques such as mindfulness, meditation, or gentle exercise may be beneficial.

In summary, the symptoms you are experiencing could be related to the medications you have taken, changes in your nervous system function, or a combination of both. A comprehensive evaluation by a healthcare professional is crucial to determine the underlying causes and to develop an appropriate treatment plan.

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