Can You Crush Quetiapine Extended Release Tablets for Easier Intake? - Psychiatry

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Can medications be crushed for consumption?


The newly packaged "Quetiapine (fumarate) Extended Release" should not be crushed or chewed, as it is designed for extended release.
Crushing the tablet can lead to a rapid release of the medication, which may increase the risk of side effects and reduce its effectiveness.
If you have difficulty swallowing the tablet, please consult your healthcare provider for alternative options or formulations that may be easier for you to take.

pinggu, 30~39 year old female. Ask Date: 2010/03/01

Dr. Su Zongwei reply Psychiatry


Crushing the medication does not change its efficacy; however, it loses the original extended-release effect.
You can discuss this issue with your physician.

Reply Date: 2010/03/01

More Info


When it comes to taking Quetiapine Extended Release (ER) tablets, it is crucial to understand the implications of altering the form of the medication. Quetiapine ER is designed with a special coating that allows for a controlled release of the medication over time. This means that the drug is intended to be absorbed slowly into the bloodstream, providing a steady effect throughout the day. Crushing or chewing the tablets can disrupt this mechanism, leading to a rapid release of the medication, which can increase the risk of side effects and reduce the overall effectiveness of the treatment.

The concern about crushing Quetiapine ER tablets is not just about the immediate effects but also about the potential for increased side effects. When the medication is released too quickly, it can lead to higher peak levels of the drug in the bloodstream, which may result in increased sedation, dizziness, or other adverse effects. Additionally, the risk of experiencing withdrawal symptoms or rebound effects may also be heightened if the medication is not taken as prescribed.

If you are having difficulty swallowing the tablets, it is essential to discuss this with your healthcare provider. They may be able to suggest alternative formulations of the medication, such as a liquid form or a different medication that is easier to swallow. It is also important to consider that there are various strategies to help with swallowing pills, such as using a pill crusher or swallowing aids, but these should be discussed with a healthcare professional to ensure they are safe and effective.

In your case, since you have been taking Quetiapine for an extended period without significant side effects, it is understandable that you may be hesitant to switch medications. However, it is vital to prioritize your safety and the effectiveness of your treatment. If you are experiencing challenges with swallowing the tablets, please reach out to your doctor or pharmacist for guidance. They can provide you with the best options tailored to your specific needs.

Moreover, if you have been prescribed Quetiapine for conditions such as schizophrenia, bipolar disorder, or major depressive disorder, it is essential to maintain open communication with your healthcare provider regarding any side effects or concerns you may have. They can help monitor your treatment and make necessary adjustments to ensure that you are receiving the best care possible.

In summary, do not crush Quetiapine Extended Release tablets, as this can lead to unintended consequences. Instead, consult your healthcare provider for alternative solutions that will allow you to take your medication safely and effectively. Your health and well-being should always come first, and there are often multiple ways to address medication challenges without compromising your treatment plan.

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