Why Does Sweet Food Taste Bitter Suddenly? a Medical Mystery - Internal Medicine

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Why does sweet food taste bitter now?


Hello! My dad has recently experienced a strange issue where anything sweet he eats tastes very bitter, while salty or spicy foods taste normal.
This problem has suddenly appeared, and it didn't exist before.
He took cold medicine in the morning, which seemed to help a bit, but after not taking it in the afternoon, the bitterness returned.
Could you please help me understand what's going on? Thank you!

Zhu, 20~29 year old female. Ask Date: 2010/05/22

Dr. Li Zhiyao reply Internal Medicine


Hello: Taste bud cells in humans gradually atrophy with aging, leading to a decline in taste perception.
Additionally, diseases, medications, surgical procedures, environmental factors, and nutritional deficiencies (such as zinc deficiency) can also affect taste sensitivity.
Some elderly individuals may notice changes in flavor or a reduced sensitivity to taste stimuli.
They may experience a lack of flavor, diminished taste, or a persistent bitter or unusual taste regardless of what they eat.
Some may even feel a bitter sensation in their mouths when not eating.
It is important to be aware of systemic diseases such as diabetes, kidney disease, liver disease, which can complicate neuropathy, as well as facial nerve disorders, or reduced saliva production (due to disease, medication side effects, or aging).
Other significant causes include taste perception difficulties associated with olfactory abnormalities and taste disorders caused by depression.

Reply Date: 2010/05/22

More Info


The sudden change in taste perception, particularly the experience of sweet foods tasting bitter, can be perplexing and concerning. This phenomenon, known as dysgeusia, can be attributed to various factors, including medication effects, underlying health conditions, or even psychological influences.

Firstly, medications can significantly alter taste perception. Certain drugs, especially those used to treat conditions like hypertension, depression, or infections, can lead to changes in how flavors are perceived. For instance, some antibiotics and antihistamines are known to cause a metallic or bitter taste in the mouth. If your father recently started a new medication or changed dosages, this could be a contributing factor. It’s essential to review any medications he is taking with a healthcare provider to determine if they could be responsible for this change in taste.

Secondly, underlying health conditions can also play a role. Conditions such as sinus infections, allergies, or oral health issues can affect taste. For example, a sinus infection can lead to a loss of smell, which is closely linked to taste perception. Additionally, oral health problems, such as gum disease or tooth decay, can alter taste sensations. If your father has been experiencing other symptoms, such as nasal congestion or oral discomfort, it may be worthwhile to consult a healthcare professional.

Another potential cause is the presence of systemic conditions, such as diabetes or neurological disorders. Diabetes can lead to taste changes due to fluctuations in blood sugar levels, while neurological conditions can affect the nerves responsible for taste sensation. If your father has a history of such conditions, it would be prudent to discuss these changes with his doctor.

Psychological factors, including stress and depression, can also influence taste perception. The brain plays a crucial role in how we perceive flavors, and emotional states can alter this perception. If your father has been under significant stress or experiencing mood changes, this could contribute to his altered taste sensations.

In your father's case, the fact that sweet foods taste bitter while salty or spicy foods do not suggests a selective alteration in taste perception. This could indicate a localized issue, such as a reaction to a specific food or ingredient, or it could be related to the aforementioned factors. The temporary improvement after taking cold medicine may suggest that inflammation or congestion is affecting his taste perception, as some cold medications can reduce sinus pressure and improve overall sensory function.

Given these possibilities, it is advisable for your father to consult a healthcare professional, particularly an ear, nose, and throat (ENT) specialist or a neurologist, to explore the underlying causes of his symptoms. A thorough evaluation, including a review of his medical history, medication use, and any accompanying symptoms, will help determine the appropriate course of action.

In summary, the sudden bitterness of sweet foods can arise from various factors, including medication side effects, underlying health conditions, and psychological influences. A comprehensive evaluation by a healthcare professional is essential to identify the cause and provide appropriate management.

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