Gastroesophageal reflux disease (GERD)
Hello: The gastroscopy examination shows NERD...
I am currently taking Nexium, and my symptoms are under control (purchased out of pocket)...
May I ask when I can gradually switch to FOMA? How long should I take FOMA? Once the symptoms are resolved, can I stop the medication? Or how long after the symptoms disappear can I discontinue the medication? Thank you.
Michael, 40~49 year old female. Ask Date: 2010/05/31
Dr. Chen Qifeng reply Gastroenterology and Hepatology
Hello, generally speaking, the efficacy of PPIs (such as Nexium) far exceeds that of H2 blockers (such as FOMA) for both NERD and GERD.
Based on accumulated clinical experience, it is now believed that the role of H2 blockers in reflux esophagitis is diminishing.
After symptom relief, some physicians advocate for a "use as needed" approach.
Wishing you health, Dr.
Chen Qi-Feng, Taoyuan Hospital, Department of Health.
Reply Date: 2010/05/31
More Info
Managing gastroesophageal reflux disease (GERD) can be a complex process, especially when transitioning between different medications like Nexium (esomeprazole) and FOMA (famotidine). Both medications serve to reduce stomach acid, but they do so through different mechanisms and are classified into different categories of acid-reducing agents. Nexium is a proton pump inhibitor (PPI), while FOMA is an H2 receptor antagonist.
Transitioning from Nexium to FOMA
When considering a transition from Nexium to FOMA, it is essential to consult with your healthcare provider. The timing of this transition can depend on several factors, including the severity of your symptoms, how well they are controlled on Nexium, and your overall health status. Generally, if your symptoms are well-managed with Nexium, your doctor may suggest a gradual tapering off of Nexium before starting FOMA. This approach helps to minimize the risk of rebound acid hypersecretion, which can occur when stopping PPIs suddenly.
Duration of FOMA Treatment
The duration for which you should take FOMA can vary based on your individual circumstances. Typically, H2 blockers like FOMA can be used for a longer duration than PPIs, but the exact length of treatment should be determined by your healthcare provider. If your symptoms improve and you feel stable, your doctor may suggest a trial period of discontinuation after a certain duration of treatment. This could be anywhere from a few weeks to several months, depending on your response to the medication.
Stopping Medication After Symptom Resolution
If your symptoms have resolved while taking FOMA, your healthcare provider may recommend tapering off the medication rather than stopping it abruptly. This gradual reduction can help assess whether your symptoms return and whether you might need to resume treatment. It is generally advised to monitor your symptoms closely after discontinuation. If symptoms reappear, it may indicate that you need to restart treatment or consider alternative long-term management strategies.
Long-term Management of GERD
For many individuals with GERD, long-term management may be necessary, even after symptoms have improved. This could involve lifestyle modifications, such as dietary changes, weight management, and avoiding triggers that exacerbate symptoms. Some patients may find that they can manage their symptoms with intermittent use of medications rather than continuous daily treatment.
Conclusion
In summary, transitioning from Nexium to FOMA should be done under the guidance of your healthcare provider, who can help determine the appropriate timing and duration of treatment. While FOMA can be effective for managing GERD symptoms, the decision to stop medication should be made based on your response and in consultation with your doctor. Regular follow-ups and monitoring of symptoms are crucial in managing GERD effectively. If you have any concerns or experience any new symptoms, do not hesitate to reach out to your healthcare provider for further evaluation and guidance.
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